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Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern.
Sathler-Avelar R, Vitelli-Avelar DM, Massara RL, de Lana M, Pinto Dias JC, Teixeira-Carvalho A, Elói-Santos SM, Martins-Filho OA. Sathler-Avelar R, et al. Microbes Infect. 2008 Feb;10(2):103-13. doi: 10.1016/j.micinf.2007.10.009. Epub 2007 Oct 22. Microbes Infect. 2008. PMID: 18248755 Free article.
Regulatory T cells phenotype in different clinical forms of Chagas' disease.
de Araújo FF, Vitelli-Avelar DM, Teixeira-Carvalho A, Antas PR, Assis Silva Gomes J, Sathler-Avelar R, Otávio Costa Rocha M, Elói-Santos SM, Pinho RT, Correa-Oliveira R, Martins-Filho OA. de Araújo FF, et al. PLoS Negl Trop Dis. 2011;5(5):e992. doi: 10.1371/journal.pntd.0000992. Epub 2011 May 31. PLoS Negl Trop Dis. 2011. PMID: 21655351 Free PMC article. Review.
Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease.
Vitelli-Avelar DM, Sathler-Avelar R, Mattoso-Barbosa AM, Gouin N, Perdigão-de-Oliveira M, Valério-Dos-Reis L, Costa RP, Elói-Santos SM, Gomes MS, Amaral LR, Teixeira-Carvalho A, Martins-Filho OA, Dick EJ Jr, Hubbard GB, VandeBerg JF, VandeBerg JL. Vitelli-Avelar DM, et al. Among authors: sathler avelar r. PLoS Negl Trop Dis. 2017 Feb 22;11(2):e0005233. doi: 10.1371/journal.pntd.0005233. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28225764 Free PMC article.
Are increased frequency of macrophage-like and natural killer (NK) cells, together with high levels of NKT and CD4+CD25high T cells balancing activated CD8+ T cells, the key to control Chagas' disease morbidity?
Vitelli-Avelar DM, Sathler-Avelar R, Massara RL, Borges JD, Lage PS, Lana M, Teixeira-Carvalho A, Dias JC, Elói-Santos SM, Martins-Filho OA. Vitelli-Avelar DM, et al. Clin Exp Immunol. 2006 Jul;145(1):81-92. doi: 10.1111/j.1365-2249.2006.03123.x. Clin Exp Immunol. 2006. PMID: 16792677 Free PMC article.
Benznidazole treatment during early-indeterminate Chagas' disease shifted the cytokine expression by innate and adaptive immunity cells toward a type 1-modulated immune profile.
Sathler-Avelar R, Vitelli-Avelar DM, Massara RL, Borges JD, Lana M, Teixeira-Carvalho A, Dias JC, Elói-Santos SM, Martins-Filho OA. Sathler-Avelar R, et al. Scand J Immunol. 2006 Nov;64(5):554-63. doi: 10.1111/j.1365-3083.2006.01843.x. Scand J Immunol. 2006. PMID: 17032249 Free article. Clinical Trial.
Impaired phagocytic capacity driven by downregulation of major phagocytosis-related cell surface molecules elicits an overall modulatory cytokine profile in neutrophils and monocytes from the indeterminate clinical form of Chagas disease.
Gomes JA, Campi-Azevedo AC, Teixeira-Carvalho A, Silveira-Lemos D, Vitelli-Avelar D, Sathler-Avelar R, Peruhype-Magalhães V, Silvestre KF, Batista MA, Schachnik NC, Correa-Oliveira R, Eloi-Santos S, Martins-Filho OA. Gomes JA, et al. Immunobiology. 2012 Oct;217(10):1005-16. doi: 10.1016/j.imbio.2012.01.014. Epub 2012 Jan 20. Immunobiology. 2012. PMID: 22387073
27 results