Maxwell A - Search Results

1

DNA gyrase from the albicidin producer Xanthomonas albilineans has multiple-antibiotic-resistance and unusual enzymatic properties.

Hashimi SM, Huang G, Maxwell A, Birch RG. Hashimi SM, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2008 Apr;52(4):1382-90. doi: 10.1128/AAC.01551-07. Epub 2008 Feb 11. Antimicrob Agents Chemother. 2008. PMID: 18268084 Free PMC article.

2

Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins.

Hallett P, Maxwell A. Hallett P, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 1991 Feb;35(2):335-40. doi: 10.1128/AAC.35.2.335. Antimicrob Agents Chemother. 1991. PMID: 1850970 Free PMC article.

3

A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex.

Willmott CJ, Maxwell A. Willmott CJ, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 1993 Jan;37(1):126-7. doi: 10.1128/AAC.37.1.126. Antimicrob Agents Chemother. 1993. PMID: 8381633 Free PMC article.

4

Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87).

Barnard FM, Maxwell A. Barnard FM, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2001 Jul;45(7):1994-2000. doi: 10.1128/AAC.45.7.1994-2000.2001. Antimicrob Agents Chemother. 2001. PMID: 11408214 Free PMC article.

5

Quinolone-binding pocket of DNA gyrase: role of GyrB.

Heddle J, Maxwell A. Heddle J, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2002 Jun;46(6):1805-15. doi: 10.1128/AAC.46.6.1805-1815.2002. Antimicrob Agents Chemother. 2002. PMID: 12019094 Free PMC article.

6

Importance of the fourth alpha-helix within the CAP homology domain of type II topoisomerase for DNA cleavage site recognition and quinolone action.

Strumberg D, Nitiss JL, Dong J, Walker J, Nicklaus MC, Kohn KW, Heddle JG, Maxwell A, Seeber S, Pommier Y. Strumberg D, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2002 Sep;46(9):2735-46. doi: 10.1128/AAC.46.9.2735-2746.2002. Antimicrob Agents Chemother. 2002. PMID: 12183223 Free PMC article.

7

Quinolone-DNA interaction: sequence-dependent binding to single-stranded DNA reflects the interaction within the gyrase-DNA complex.

Noble CG, Barnard FM, Maxwell A. Noble CG, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2003 Mar;47(3):854-62. doi: 10.1128/AAC.47.3.854-862.2003. Antimicrob Agents Chemother. 2003. PMID: 12604512 Free PMC article.

8

A mutation in Escherichia coli DNA gyrase conferring quinolone resistance results in sensitivity to drugs targeting eukaryotic topoisomerase II.

Gruger T, Nitiss JL, Maxwell A, Zechiedrich EL, Heisig P, Seeber S, Pommier Y, Strumberg D. Gruger T, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2004 Dec;48(12):4495-504. doi: 10.1128/AAC.48.12.4495-4504.2004. Antimicrob Agents Chemother. 2004. PMID: 15561817 Free PMC article.

9

Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of action.

Flatman RH, Howells AJ, Heide L, Fiedler HP, Maxwell A. Flatman RH, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2005 Mar;49(3):1093-100. doi: 10.1128/AAC.49.3.1093-1100.2005. Antimicrob Agents Chemother. 2005. PMID: 15728908 Free PMC article.

10

The phytotoxin albicidin is a novel inhibitor of DNA gyrase.

Hashimi SM, Wall MK, Smith AB, Maxwell A, Birch RG. Hashimi SM, et al. Among authors: maxwell a. Antimicrob Agents Chemother. 2007 Jan;51(1):181-7. doi: 10.1128/AAC.00918-06. Epub 2006 Oct 30. Antimicrob Agents Chemother. 2007. PMID: 17074789 Free PMC article.

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