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The cooperating mutation or "second hit" determines the immunologic visibility toward MYC-induced murine lymphomas.
Schuster C, Berger A, Hoelzl MA, Putz EM, Frenzel A, Simma O, Moritz N, Hoelbl A, Kovacic B, Freissmuth M, Müller M, Villunger A, Müllauer L, Schmatz AI, Streubel B, Porpaczy E, Jäger U, Stoiber D, Sexl V. Schuster C, et al. Among authors: frenzel a. Blood. 2011 Oct 27;118(17):4635-45. doi: 10.1182/blood-2010-10-313098. Epub 2011 Aug 30. Blood. 2011. PMID: 21878673 Free article.
Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.
Wiegmans AP, Alsop AE, Bots M, Cluse LA, Williams SP, Banks KM, Ralli R, Scott CL, Frenzel A, Villunger A, Johnstone RW. Wiegmans AP, et al. Among authors: frenzel a. Cancer Res. 2011 May 15;71(10):3603-15. doi: 10.1158/0008-5472.CAN-10-3289. Epub 2011 Mar 11. Cancer Res. 2011. PMID: 21398407 Free article.
The MYCN oncogene and differentiation in neuroblastoma.
Westermark UK, Wilhelm M, Frenzel A, Henriksson MA. Westermark UK, et al. Among authors: frenzel a. Semin Cancer Biol. 2011 Oct;21(4):256-66. doi: 10.1016/j.semcancer.2011.08.001. Epub 2011 Aug 9. Semin Cancer Biol. 2011. PMID: 21849159 Review.
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.
Zirath H, Frenzel A, Oliynyk G, Segerström L, Westermark UK, Larsson K, Munksgaard Persson M, Hultenby K, Lehtiö J, Einvik C, Påhlman S, Kogner P, Jakobsson PJ, Henriksson MA. Zirath H, et al. Among authors: frenzel a. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10258-63. doi: 10.1073/pnas.1222404110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733953 Free PMC article.
Targeting of the MYCN protein with small molecule c-MYC inhibitors.
Müller I, Larsson K, Frenzel A, Oliynyk G, Zirath H, Prochownik EV, Westwood NJ, Henriksson MA. Müller I, et al. Among authors: frenzel a. PLoS One. 2014 May 23;9(5):e97285. doi: 10.1371/journal.pone.0097285. eCollection 2014. PLoS One. 2014. PMID: 24859015 Free PMC article.
Targeting MYC-Regulated miRNAs to Combat Cancer.
Frenzel A, Lovén J, Henriksson MA. Frenzel A, et al. Genes Cancer. 2010 Jun;1(6):660-7. doi: 10.1177/1947601910377488. Genes Cancer. 2010. PMID: 21779463 Free PMC article.
127 results