Fletcher J - Search Results

1

Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, Walsh K, Sweeney C, Leavy O, Fletcher J, Lavelle EC, Dunne P, Mills KH. Jarnicki AG, et al. Among authors: fletcher j. J Immunol. 2008 Mar 15;180(6):3797-806. doi: 10.4049/jimmunol.180.6.3797. J Immunol. 2008. PMID: 18322186

2

Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

Taams LS, Vukmanovic-Stejic M, Smith J, Dunne PJ, Fletcher JM, Plunkett FJ, Ebeling SB, Lombardi G, Rustin MH, Bijlsma JW, Lafeber FP, Salmon M, Akbar AN. Taams LS, et al. Among authors: fletcher jm. Eur J Immunol. 2002 Jun;32(6):1621-30. doi: 10.1002/1521-4141(200206)32:6<1621::AID-IMMU1621>3.0.CO;2-Q. Eur J Immunol. 2002. PMID: 12115645 Free article.

3

Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential.

Dunne PJ, Faint JM, Gudgeon NH, Fletcher JM, Plunkett FJ, Soares MV, Hislop AD, Annels NE, Rickinson AB, Salmon M, Akbar AN. Dunne PJ, et al. Among authors: fletcher jm. Blood. 2002 Aug 1;100(3):933-40. doi: 10.1182/blood-2002-01-0160. Blood. 2002. PMID: 12130505 Free article.

4

Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.

Fletcher JM, Vukmanovic-Stejic M, Dunne PJ, Birch KE, Cook JE, Jackson SE, Salmon M, Rustin MH, Akbar AN. Fletcher JM, et al. J Immunol. 2005 Dec 15;175(12):8218-25. doi: 10.4049/jimmunol.175.12.8218. J Immunol. 2005. PMID: 16339561

5

Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta.

Rowan AG, Fletcher JM, Ryan EJ, Moran B, Hegarty JE, O'Farrelly C, Mills KH. Rowan AG, et al. Among authors: fletcher jm. J Immunol. 2008 Oct 1;181(7):4485-94. doi: 10.4049/jimmunol.181.7.4485. J Immunol. 2008. PMID: 18802051

6

CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis.

Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, O'Farrelly C, Tubridy N, Mills KH. Fletcher JM, et al. J Immunol. 2009 Dec 1;183(11):7602-10. doi: 10.4049/jimmunol.0901881. Epub 2009 Nov 16. J Immunol. 2009. PMID: 19917691

7

OAS1: a multiple sclerosis susceptibility gene that influences disease severity.

O'Brien M, Lonergan R, Costelloe L, O'Rourke K, Fletcher JM, Kinsella K, Sweeney C, Antonelli G, Mills KH, O'Farrelly C, Hutchinson M, Tubridy N. O'Brien M, et al. Among authors: fletcher jm. Neurology. 2010 Aug 3;75(5):411-8. doi: 10.1212/WNL.0b013e3181ebdd2b. Neurology. 2010. PMID: 20679634

8

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

Fletcher JM, Lalor SJ, Sweeney CM, Tubridy N, Mills KH. Fletcher JM, et al. Clin Exp Immunol. 2010 Oct;162(1):1-11. doi: 10.1111/j.1365-2249.2010.04143.x. Clin Exp Immunol. 2010. PMID: 20682002 Free PMC article. Review.

9

Recent advances in regulatory T cell therapy of autoimmunity, graft rejection and cancer.

Dunne PJ, Fletcher JM. Dunne PJ, et al. Among authors: fletcher jm. Recent Pat Inflamm Allergy Drug Discov. 2010 Nov;4(3):231-43. doi: 10.2174/187221310793564182. Recent Pat Inflamm Allergy Drug Discov. 2010. PMID: 20812898 Review.

10

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells.

Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM. Sweeney CM, et al. Among authors: fletcher jm. Brain Behav Immun. 2011 Aug;25(6):1170-81. doi: 10.1016/j.bbi.2011.03.007. Epub 2011 Mar 21. Brain Behav Immun. 2011. PMID: 21420486

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