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Design and activity of a murine and humanized anti-CEACAM6 single-chain variable fragment in the treatment of pancreatic cancer.
Riley CJ, Engelhardt KP, Saldanha JW, Qi W, Cooke LS, Zhu Y, Narayan ST, Shakalya K, Croce KD, Georgiev IG, Nagle RB, Garewal H, Von Hoff DD, Mahadevan D. Riley CJ, et al. Among authors: mahadevan d. Cancer Res. 2009 Mar 1;69(5):1933-40. doi: 10.1158/0008-5472.CAN-08-2707. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244123 Free PMC article.
Alisertib (MLN8237) an investigational agent suppresses Aurora A and B activity, inhibits proliferation, promotes endo-reduplication and induces apoptosis in T-NHL cell lines supporting its importance in PTCL treatment.
Qi W, Spier C, Liu X, Agarwal A, Cooke LS, Persky DO, Chen D, Miller TP, Mahadevan D. Qi W, et al. Among authors: mahadevan d. Leuk Res. 2013 Apr;37(4):434-9. doi: 10.1016/j.leukres.2012.10.017. Epub 2012 Nov 12. Leuk Res. 2013. PMID: 23153524 Free PMC article.
Discovery of a novel class of AKT pleckstrin homology domain inhibitors.
Mahadevan D, Powis G, Mash EA, George B, Gokhale VM, Zhang S, Shakalya K, Du-Cuny L, Berggren M, Ali MA, Jana U, Ihle N, Moses S, Franklin C, Narayan S, Shirahatti N, Meuillet EJ. Mahadevan D, et al. Mol Cancer Ther. 2008 Sep;7(9):2621-32. doi: 10.1158/1535-7163.MCT-07-2276. Mol Cancer Ther. 2008. PMID: 18790745 Free PMC article.
189 results