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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Karikó K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J. Kleinman ME, et al. Among authors: sakurai e. Nature. 2008 Apr 3;452(7187):591-7. doi: 10.1038/nature06765. Epub 2008 Mar 26. Nature. 2008. PMID: 18368052 Free PMC article.
Corneal avascularity is due to soluble VEGF receptor-1.
Ambati BK, Nozaki M, Singh N, Takeda A, Jani PD, Suthar T, Albuquerque RJ, Richter E, Sakurai E, Newcomb MT, Kleinman ME, Caldwell RB, Lin Q, Ogura Y, Orecchia A, Samuelson DA, Agnew DW, St Leger J, Green WR, Mahasreshti PJ, Curiel DT, Kwan D, Marsh H, Ikeda S, Leiper LJ, Collinson JM, Bogdanovich S, Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J. Ambati BK, et al. Among authors: sakurai e. Nature. 2006 Oct 26;443(7114):993-7. doi: 10.1038/nature05249. Epub 2006 Oct 18. Nature. 2006. PMID: 17051153 Free PMC article.
Drusen complement components C3a and C5a promote choroidal neovascularization.
Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J. Nozaki M, et al. Among authors: sakurai e. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2328-33. doi: 10.1073/pnas.0408835103. Epub 2006 Feb 1. Proc Natl Acad Sci U S A. 2006. PMID: 16452172 Free PMC article.
271 results