Cecchi A - Search Results

1

Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.

Temperini C, Cecchi A, Scozzafava A, Supuran CT. Temperini C, et al. Among authors: cecchi a. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2567-73. doi: 10.1016/j.bmcl.2008.03.051. Epub 2008 Mar 20. Bioorg Med Chem Lett. 2008. PMID: 18374572

2

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.

Cecchi A, Winum JY, Innocenti A, Vullo D, Montero JL, Scozzafava A, Supuran CT. Cecchi A, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5775-80. doi: 10.1016/j.bmcl.2004.09.062. Bioorg Med Chem Lett. 2004. PMID: 15501039

3

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.

Puccetti L, Fasolis G, Cecchi A, Winum JY, Gamberi A, Montero JL, Scozzafava A, Supuran CT. Puccetti L, et al. Among authors: cecchi a. Bioorg Med Chem Lett. 2005 May 2;15(9):2359-64. doi: 10.1016/j.bmcl.2005.02.087. Bioorg Med Chem Lett. 2005. PMID: 15837325

4

Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxic tumors.

Winum JY, Cecchi A, Montero JL, Innocenti A, Scozzafava A, Supuran CT. Winum JY, et al. Among authors: cecchi a. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3302-6. doi: 10.1016/j.bmcl.2005.04.058. Bioorg Med Chem Lett. 2005. PMID: 15908201

5

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

Cecchi A, Hulikova A, Pastorek J, Pastoreková S, Scozzafava A, Winum JY, Montero JL, Supuran CT. Cecchi A, et al. J Med Chem. 2005 Jul 28;48(15):4834-41. doi: 10.1021/jm0501073. J Med Chem. 2005. PMID: 16033263

6

Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.

Cecchi A, Taylor SD, Liu Y, Hill B, Vullo D, Scozzafava A, Supuran CT. Cecchi A, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5192-6. doi: 10.1016/j.bmcl.2005.08.102. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16203142

7

Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX.

Thiry A, Ledecq M, Cecchi A, Dogné JM, Wouters J, Supuran CT, Masereel B. Thiry A, et al. Among authors: cecchi a. J Med Chem. 2006 May 4;49(9):2743-9. doi: 10.1021/jm0600287. J Med Chem. 2006. PMID: 16640335

8

Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX.

Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT. Alterio V, et al. Among authors: cecchi a. J Am Chem Soc. 2006 Jun 28;128(25):8329-35. doi: 10.1021/ja061574s. J Am Chem Soc. 2006. PMID: 16787097

9

Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.

Nishimori I, Minakuchi T, Onishi S, Vullo D, Cecchi A, Scozzafava A, Supuran CT. Nishimori I, et al. Among authors: cecchi a. Bioorg Med Chem. 2007 Dec 1;15(23):7229-36. doi: 10.1016/j.bmc.2007.08.037. Epub 2007 Aug 25. Bioorg Med Chem. 2007. PMID: 17826101

10

Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.

Temperini C, Cecchi A, Boyle NA, Scozzafava A, Cabeza JE, Wentworth P Jr, Blackburn GM, Supuran CT. Temperini C, et al. Among authors: cecchi a. Bioorg Med Chem Lett. 2008 Feb 1;18(3):999-1005. doi: 10.1016/j.bmcl.2007.12.022. Epub 2007 Dec 15. Bioorg Med Chem Lett. 2008. PMID: 18162396

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