Li W - Search Results

1

Solution structure of wild-type human matrix metalloproteinase 12 (MMP-12) in complex with a tight-binding inhibitor.

Markus MA, Dwyer B, Wolfrom S, Li J, Li W, Malakian K, Wilhelm J, Tsao DH. Markus MA, et al. Among authors: li j, li w. J Biomol NMR. 2008 May;41(1):55-60. doi: 10.1007/s10858-008-9236-4. Epub 2008 Apr 19. J Biomol NMR. 2008. PMID: 18425585 No abstract available.

2

1H, 13C, and 15N assignments of MMP-12, a key protease implicated in lung tissue remodeling.

Markus MA, Dwyer B, Wolfrom S, Li J, Li W, Malakian K, Wilhelm J, Tsao DH. Markus MA, et al. Among authors: li j, li w. J Biomol NMR. 2005 Mar;31(3):260. doi: 10.1007/s10858-005-0181-1. J Biomol NMR. 2005. PMID: 15803400 No abstract available.

3

Mechanistic pathways in CF3COOH-mediated deacetalization reactions.

Li W, Li J, Wu Y, Fuller N, Markus MA. Li W, et al. Among authors: li j. J Org Chem. 2010 Feb 19;75(4):1077-86. doi: 10.1021/jo902014z. J Org Chem. 2010. PMID: 20095540

4

3,4-Disubstituted benzofuran P1' MMP-13 inhibitors: optimization of selectivity and reduction of protein binding.

Li W, Hu Y, Li J, Thomason JR, DeVincentis D, Du X, Wu J, Hotchandani R, Rush TS 3rd, Skotnicki JS, Tam S, Chockalingam PS, Morris EA, Levin JI. Li W, et al. Among authors: li j. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4546-50. doi: 10.1016/j.bmcl.2009.07.008. Epub 2009 Jul 9. Bioorg Med Chem Lett. 2009. PMID: 19625186

5

Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma.

Li W, Li J, Wu Y, Rancati F, Vallese S, Raveglia L, Wu J, Hotchandani R, Fuller N, Cunningham K, Morgan P, Fish S, Krykbaev R, Xu X, Tam S, Goldman SJ, Abraham W, Williams C, Sypek J, Mansour TS. Li W, et al. Among authors: li j. J Med Chem. 2009 Sep 10;52(17):5408-19. doi: 10.1021/jm900809r. J Med Chem. 2009. PMID: 19725580

6

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.

Hu Y, Xiang JS, DiGrandi MJ, Du X, Ipek M, Laakso LM, Li J, Li W, Rush TS, Schmid J, Skotnicki JS, Tam S, Thomason JR, Wang Q, Levin JI. Hu Y, et al. Among authors: li j, li w. Bioorg Med Chem. 2005 Dec 15;13(24):6629-44. doi: 10.1016/j.bmc.2005.07.076. Epub 2005 Oct 10. Bioorg Med Chem. 2005. PMID: 16216515

7

Dimethyl sulfoxide mediated elimination reactions in 3-aryl 2,3-dihalopropanoates: scope and mechanistic insights.

Li W, Li J, Lin M, Wacharasindhu S, Tabei K, Mansour TS. Li W, et al. Among authors: li j. J Org Chem. 2007 Aug 3;72(16):6016-21. doi: 10.1021/jo070217c. Epub 2007 Jul 12. J Org Chem. 2007. PMID: 17628103

8

Synthesis and SAR of highly selective MMP-13 inhibitors.

Li J, Rush TS 3rd, Li W, DeVincentis D, Du X, Hu Y, Thomason JR, Xiang JS, Skotnicki JS, Tam S, Cunningham KM, Chockalingam PS, Morris EA, Levin JI. Li J, et al. Among authors: li w. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4961-6. doi: 10.1016/j.bmcl.2005.08.001. Bioorg Med Chem Lett. 2005. PMID: 16153831

9

Preparation of alpha-haloacrylate derivatives via dimethyl sulfoxide-mediated selective dehydrohalogenation.

Li W, Li J, Wan ZK, Wu J, Massefski W. Li W, et al. Among authors: li j. Org Lett. 2007 Oct 25;9(22):4607-10. doi: 10.1021/ol7021142. Epub 2007 Oct 2. Org Lett. 2007. PMID: 17910466

10

Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD).

Wu Y, Li J, Wu J, Morgan P, Xu X, Rancati F, Vallese S, Raveglia L, Hotchandani R, Fuller N, Bard J, Cunningham K, Fish S, Krykbaev R, Tam S, Goldman SJ, Williams C, Mansour TS, Saiah E, Sypek J, Li W. Wu Y, et al. Among authors: li j, li w. Bioorg Med Chem Lett. 2012 Jan 1;22(1):138-43. doi: 10.1016/j.bmcl.2011.11.046. Epub 2011 Nov 20. Bioorg Med Chem Lett. 2012. PMID: 22153340

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