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ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.
Oskolkova OV, Afonyushkin T, Leitner A, von Schlieffen E, Gargalovic PS, Lusis AJ, Binder BR, Bochkov VN. Oskolkova OV, et al. Among authors: afonyushkin t. Blood. 2008 Jul 15;112(2):330-9. doi: 10.1182/blood-2007-09-112870. Epub 2008 May 1. Blood. 2008. PMID: 18451308 Free PMC article.
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions.
Bochkov VN, Philippova M, Oskolkova O, Kadl A, Furnkranz A, Karabeg E, Afonyushkin T, Gruber F, Breuss J, Minchenko A, Mechtcheriakova D, Hohensinner P, Rychli K, Wojta J, Resink T, Erne P, Binder BR, Leitinger N. Bochkov VN, et al. Among authors: afonyushkin t. Circ Res. 2006 Oct 13;99(8):900-8. doi: 10.1161/01.RES.0000245485.04489.ee. Epub 2006 Sep 14. Circ Res. 2006. PMID: 16973904
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.
Afonyushkin T, Oskolkova OV, Philippova M, Resink TJ, Erne P, Binder BR, Bochkov VN. Afonyushkin T, et al. Arterioscler Thromb Vasc Biol. 2010 May;30(5):1007-13. doi: 10.1161/ATVBAHA.110.204354. Epub 2010 Feb 25. Arterioscler Thromb Vasc Biol. 2010. PMID: 20185790
35 results