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Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, and biological activities.
Di Santo R, Costi R, Roux A, Miele G, Crucitti GC, Iacovo A, Rosi F, Lavecchia A, Marinelli L, Di Giovanni C, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: novellino e. J Med Chem. 2008 Aug 14;51(15):4744-50. doi: 10.1021/jm8001422. Epub 2008 Jul 23. J Med Chem. 2008. PMID: 18646746 Free PMC article.
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action.
Di Santo R, Costi R, Roux A, Artico M, Lavecchia A, Marinelli L, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: novellino e. J Med Chem. 2006 Mar 23;49(6):1939-45. doi: 10.1021/jm0511583. J Med Chem. 2006. PMID: 16539381 Free PMC article.
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
Costi R, Crucitti GC, Pescatori L, Messore A, Scipione L, Tortorella S, Amoroso A, Crespan E, Campiglia P, Maresca B, Porta A, Granata I, Novellino E, Gouge J, Delarue M, Maga G, Di Santo R. Costi R, et al. Among authors: novellino e. J Med Chem. 2013 Sep 26;56(18):7431-41. doi: 10.1021/jm4010187. Epub 2013 Sep 12. J Med Chem. 2013. PMID: 23968551
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach.
Costi R, Métifiot M, Esposito F, Cuzzucoli Crucitti G, Pescatori L, Messore A, Scipione L, Tortorella S, Zinzula L, Novellino E, Pommier Y, Tramontano E, Marchand C, Di Santo R. Costi R, et al. Among authors: novellino e. J Med Chem. 2013 Nov 14;56(21):8588-98. doi: 10.1021/jm401040b. Epub 2013 Nov 5. J Med Chem. 2013. PMID: 24124919 Free PMC article.
740 results