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E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor.
Takahashi M, Sato T, Sagawa T, Lu Y, Sato Y, Iyama S, Yamada Y, Fukaura J, Takahashi S, Miyanishi K, Yamashita T, Sasaki K, Kogawa K, Hamada H, Kato J, Niitsu Y. Takahashi M, et al. Among authors: takahashi s. Mol Ther. 2002 May;5(5 Pt 1):627-34. doi: 10.1006/mthe.2002.0589. Mol Ther. 2002. PMID: 11991754 Free article.
Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter.
Sagawa T, Takahashi M, Sato T, Sato Y, Lu Y, Sumiyoshi T, Yamada Y, Iyama S, Fukaura J, Sasaki K, Hamada H, Miyanishi K, Takayama T, Kato J, Niitsu Y. Sagawa T, et al. Among authors: takahashi m. Mol Ther. 2004 Dec;10(6):1043-50. doi: 10.1016/j.ymthe.2004.08.023. Mol Ther. 2004. PMID: 15564136 Free article.
Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells.
Sato T, Machida T, Takahashi S, Iyama S, Sato Y, Kuribayashi K, Takada K, Oku T, Kawano Y, Okamoto T, Takimoto R, Matsunaga T, Takayama T, Takahashi M, Kato J, Niitsu Y. Sato T, et al. Among authors: takahashi m, takahashi s. J Immunol. 2004 Jul 1;173(1):285-96. doi: 10.4049/jimmunol.173.1.285. J Immunol. 2004. PMID: 15210786
Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.
Sato Y, Araki H, Kato J, Nakamura K, Kawano Y, Kobune M, Sato T, Miyanishi K, Takayama T, Takahashi M, Takimoto R, Iyama S, Matsunaga T, Ohtani S, Matsuura A, Hamada H, Niitsu Y. Sato Y, et al. Among authors: takahashi m. Blood. 2005 Jul 15;106(2):756-63. doi: 10.1182/blood-2005-02-0572. Epub 2005 Apr 7. Blood. 2005. PMID: 15817682 Free article.
A Phase I trial of arterial infusion chemotherapy with gemcitabine and 5-fluorouracil for unresectable advanced pancreatic cancer after vascular supply distribution via superselective embolization.
Miyanishi K, Ishiwatari H, Hayashi T, Takahashi M, Kawano Y, Takada K, Ihara H, Okuda T, Takanashi K, Takahashi S, Sato Y, Matsunaga T, Homma H, Kato J, Niitsu Y. Miyanishi K, et al. Among authors: takahashi m, takahashi s. Jpn J Clin Oncol. 2008 Apr;38(4):268-74. doi: 10.1093/jjco/hyn015. Epub 2008 Mar 28. Jpn J Clin Oncol. 2008. PMID: 18375446 Clinical Trial.
A phase II study of neoadjuvant combination chemotherapy with docetaxel, cisplatin, and S-1 for locally advanced resectable gastric cancer: nucleotide excision repair (NER) as potential chemoresistance marker.
Hirakawa M, Sato Y, Ohnuma H, Takayama T, Sagawa T, Nobuoka T, Harada K, Miyamoto H, Sato Y, Takahashi Y, Katsuki S, Hirayama M, Takahashi M, Ono M, Maeda M, Takada K, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Hirata K, Kato J. Hirakawa M, et al. Among authors: takahashi m, takahashi y. Cancer Chemother Pharmacol. 2013 Mar;71(3):789-97. doi: 10.1007/s00280-013-2073-5. Epub 2013 Jan 22. Cancer Chemother Pharmacol. 2013. PMID: 23338051 Clinical Trial.
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