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Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity.
Hill RJ, Dabbagh K, Phippard D, Li C, Suttmann RT, Welch M, Papp E, Song KW, Chang KC, Leaffer D, Kim YN, Roberts RT, Zabka TS, Aud D, Dal Porto J, Manning AM, Peng SL, Goldstein DM, Wong BR. Hill RJ, et al. Among authors: manning am. J Pharmacol Exp Ther. 2008 Dec;327(3):610-9. doi: 10.1124/jpet.108.139006. Epub 2008 Sep 5. J Pharmacol Exp Ther. 2008. PMID: 18776065
The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells.
Song KW, Talamas FX, Suttmann RT, Olson PS, Barnett JW, Lee SW, Thompson KD, Jin S, Hekmat-Nejad M, Cai TZ, Manning AM, Hill RJ, Wong BR. Song KW, et al. Among authors: manning am. Mol Immunol. 2009 Apr;46(7):1458-66. doi: 10.1016/j.molimm.2008.12.012. Epub 2009 Jan 31. Mol Immunol. 2009. PMID: 19181383
Jun N-terminal kinase in rheumatoid arthritis.
Han Z, Boyle DL, Aupperle KR, Bennett B, Manning AM, Firestein GS. Han Z, et al. Among authors: manning am. J Pharmacol Exp Ther. 1999 Oct;291(1):124-30. J Pharmacol Exp Ther. 1999. PMID: 10490895
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase.
Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, Bhagwat SS, Manning AM, Anderson DW. Bennett BL, et al. Among authors: manning am. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13681-6. doi: 10.1073/pnas.251194298. Proc Natl Acad Sci U S A. 2001. PMID: 11717429 Free PMC article.
103 results