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Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo.
Motani A, Wang Z, Conn M, Siegler K, Zhang Y, Liu Q, Johnstone S, Xu H, Thibault S, Wang Y, Fan P, Connors R, Le H, Xu G, Walker N, Shan B, Coward P. Motani A, et al. Among authors: shan b. J Biol Chem. 2009 Mar 20;284(12):7673-80. doi: 10.1074/jbc.M809654200. Epub 2009 Jan 15. J Biol Chem. 2009. PMID: 19147488 Free PMC article.
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.
Fox BM, Sugimoto K, Iio K, Yoshida A, Zhang JK, Li K, Hao X, Labelle M, Smith ML, Rubenstein SM, Ye G, McMinn D, Jackson S, Choi R, Shan B, Ma J, Miao S, Matsui T, Ogawa N, Suzuki M, Kobayashi A, Ozeki H, Okuma C, Ishii Y, Tomimoto D, Furakawa N, Tanaka M, Matsushita M, Takahashi M, Inaba T, Sagawa S, Kayser F. Fox BM, et al. Among authors: shan b. J Med Chem. 2014 Apr 24;57(8):3464-83. doi: 10.1021/jm500135c. Epub 2014 Apr 8. J Med Chem. 2014. PMID: 24670009
Novel antineoplastic agents with efficacy against multidrug resistant tumor cells.
Medina JC, Shan B, Beckmann H, Farrell RP, Clark DL, Learned RM, Roche D, Li A, Baichwal V, Case C, Baeuerle PA, Rosen T, Jaen JC. Medina JC, et al. Among authors: shan b. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2653-6. doi: 10.1016/s0960-894x(98)00477-6. Bioorg Med Chem Lett. 1998. PMID: 9873597
FXR, a bile acid receptor and biological sensor.
Tu H, Okamoto AY, Shan B. Tu H, et al. Among authors: shan b. Trends Cardiovasc Med. 2000 Jan;10(1):30-5. doi: 10.1016/s1050-1738(00)00043-8. Trends Cardiovasc Med. 2000. PMID: 11150726 Review.
Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.
Du X, Lizarzaburu M, Turcotte S, Lee T, Greenberg J, Shan B, Fan P, Ling Y, Medina JC, Houze J. Du X, et al. Among authors: shan b. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3774-9. doi: 10.1016/j.bmcl.2011.04.053. Epub 2011 Apr 20. Bioorg Med Chem Lett. 2011. PMID: 21565497
Discovery of pyrrolopyridazines as novel DGAT1 inhibitors.
Fox BM, Iio K, Li K, Choi R, Inaba T, Jackson S, Sagawa S, Shan B, Tanaka M, Yoshida A, Kayser F. Fox BM, et al. Among authors: shan b. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6030-3. doi: 10.1016/j.bmcl.2010.08.066. Epub 2010 Aug 18. Bioorg Med Chem Lett. 2010. PMID: 20833038
1,292 results