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Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma.
Ravindranathan S, Passang T, Li JM, Wang S, Dhamsania R, Ware MB, Zaidi MY, Zhu J, Cardenas M, Liu Y, Gumber S, Robinson B, Sen-Majumdar A, Zhang H, Chandrakasan S, Kissick H, Frey AB, Thomas SN, El-Rayes BF, Lesinski GB, Waller EK. Ravindranathan S, et al. Among authors: lesinski gb. Nat Commun. 2022 Oct 27;13(1):6418. doi: 10.1038/s41467-022-34242-4. Nat Commun. 2022. PMID: 36302761 Free PMC article.
The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse.
Lesinski GB, Anghelina M, Zimmerer J, Bakalakos T, Badgwell B, Parihar R, Hu Y, Becknell B, Abood G, Chaudhury AR, Magro C, Durbin J, Carson WE 3rd. Lesinski GB, et al. J Clin Invest. 2003 Jul;112(2):170-80. doi: 10.1172/JCI16603. J Clin Invest. 2003. PMID: 12865406 Free PMC article.
Phase I study of the sequential combination of interleukin-12 and interferon alfa-2b in advanced cancer: evidence for modulation of interferon signaling pathways by interleukin-12.
Eisenbeis CF, Lesinski GB, Anghelina M, Parihar R, Valentino D, Liu J, Nadella P, Sundaram P, Young DC, Sznol M, Walker MJ, Carson WE 3rd. Eisenbeis CF, et al. Among authors: lesinski gb. J Clin Oncol. 2005 Dec 1;23(34):8835-44. doi: 10.1200/JCO.2005.02.1691. J Clin Oncol. 2005. PMID: 16314644 Clinical Trial.
137 results