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The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S. Sapieha P, et al. Among authors: mitchell g. Nat Med. 2008 Oct;14(10):1067-76. doi: 10.1038/nm.1873. Epub 2008 Oct 5. Nat Med. 2008. PMID: 18836459
Müller Cell-Localized G-Protein-Coupled Receptor 81 (Hydroxycarboxylic Acid Receptor 1) Regulates Inner Retinal Vasculature via Norrin/Wnt Pathways.
Madaan A, Chaudhari P, Nadeau-Vallée M, Hamel D, Zhu T, Mitchell G, Samuels M, Pundir S, Dabouz R, Howe Cheng CW, Mohammad Nezhady MA, Joyal JS, Rivera JC, Chemtob S. Madaan A, et al. Among authors: mitchell g. Am J Pathol. 2019 Sep;189(9):1878-1896. doi: 10.1016/j.ajpath.2019.05.016. Epub 2019 Jun 18. Am J Pathol. 2019. PMID: 31220454 Free article.
Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation.
Heckel E, Cagnone G, Agnihotri T, Cakir B, Das A, Kim JS, Kim N, Lavoie G, Situ A, Pundir S, Sun Y, Wünnemann F, Pierce KA, Dennis C, Mitchell GA, Chemtob S, Rezende FA, Andelfinger G, Clish CB, Roux PP, Sapieha P, Smith LE, Joyal JS. Heckel E, et al. Among authors: mitchell ga. JCI Insight. 2022 Mar 22;7(6):e154174. doi: 10.1172/jci.insight.154174. JCI Insight. 2022. PMID: 35167498 Free PMC article.
The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions.
Sanchez M, Hamel D, Bajon E, Duhamel F, Bhosle VK, Zhu T, Rivera JC, Dabouz R, Nadeau-Vallée M, Sitaras N, Tremblay DÉ, Omri S, Habelrih T, Rouget R, Hou X, Gobeil F, Joyal JS, Sapieha P, Mitchell G, Ribeiro-Da-Silva A, Mohammad Nezhady MA, Chemtob S. Sanchez M, et al. Among authors: mitchell g. Cells. 2022 Jul 13;11(14):2185. doi: 10.3390/cells11142185. Cells. 2022. PMID: 35883628 Free PMC article.
3,172 results