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Selective gamma-ketoaldehyde scavengers protect Nav1.5 from oxidant-induced inactivation.
Nakajima T, Davies SS, Matafonova E, Potet F, Amarnath V, Tallman KA, Serwa RA, Porter NA, Balser JR, Kupershmidt S, Roberts LJ 3rd. Nakajima T, et al. Among authors: davies ss. J Mol Cell Cardiol. 2010 Feb;48(2):352-9. doi: 10.1016/j.yjmcc.2009.11.016. Epub 2009 Dec 3. J Mol Cell Cardiol. 2010. PMID: 19962379 Free PMC article.
Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.
Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ 2nd, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT. Sidorova TN, et al. Among authors: davies ss. J Mol Cell Cardiol. 2015 Feb;79:295-302. doi: 10.1016/j.yjmcc.2014.11.013. Epub 2014 Nov 18. J Mol Cell Cardiol. 2015. PMID: 25463275 Free PMC article.
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells.
Sullivan CB, Matafonova E, Roberts LJ 2nd, Amarnath V, Davies SS. Sullivan CB, et al. Among authors: davies ss. J Lipid Res. 2010 May;51(5):999-1009. doi: 10.1194/jlr.M001040. Epub 2009 Nov 25. J Lipid Res. 2010. PMID: 19965577 Free PMC article.
106 results