Murphy SL - Search Results

1

Diverse IgG subclass responses to adeno-associated virus infection and vector administration.

Murphy SL, Li H, Mingozzi F, Sabatino DE, Hui DJ, Edmonson SA, High KA. Murphy SL, et al. J Med Virol. 2009 Jan;81(1):65-74. doi: 10.1002/jmv.21360. J Med Virol. 2009. PMID: 19031458 Free PMC article.

2

CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA. Mingozzi F, et al. Among authors: murphy sl. Nat Med. 2007 Apr;13(4):419-22. doi: 10.1038/nm1549. Epub 2007 Mar 18. Nat Med. 2007. PMID: 17369837

3

Prolonged susceptibility to antibody-mediated neutralization for adeno-associated vectors targeted to the liver.

Murphy SL, Li H, Zhou S, Schlachterman A, High KA. Murphy SL, et al. Mol Ther. 2008 Jan;16(1):138-45. doi: 10.1038/sj.mt.6300334. Epub 2007 Oct 23. Mol Ther. 2008. PMID: 17955024 Free article.

4

High-throughput screening and biophysical interrogation of hepatotropic AAV.

Murphy SL, Bhagwat A, Edmonson S, Zhou S, High KA. Murphy SL, et al. Mol Ther. 2008 Dec;16(12):1960-7. doi: 10.1038/mt.2008.210. Epub 2008 Sep 30. Mol Ther. 2008. PMID: 18827805 Free article.

5

Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

Hauck B, Murphy SL, Smith PH, Qu G, Liu X, Zelenaia O, Mingozzi F, Sommer JM, High KA, Wright JF. Hauck B, et al. Among authors: murphy sl. Mol Ther. 2009 Jan;17(1):144-52. doi: 10.1038/mt.2008.227. Epub 2008 Oct 21. Mol Ther. 2009. PMID: 18941440 Free PMC article.

6

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.

Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA. Pien GC, et al. Among authors: murphy sl. J Clin Invest. 2009 Jun;119(6):1688-95. doi: 10.1172/JCI36891. Epub 2009 May 11. J Clin Invest. 2009. PMID: 19436115 Free PMC article.

7

Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes.

Li H, Murphy SL, Giles-Davis W, Edmonson S, Xiang Z, Li Y, Lasaro MO, High KA, Ertl HC. Li H, et al. Among authors: murphy sl. Mol Ther. 2007 Apr;15(4):792-800. doi: 10.1038/sj.mt.6300090. Epub 2007 Jan 23. Mol Ther. 2007. PMID: 17245353 Free article.

8

Gene therapy for haemophilia.

Murphy SL, High KA. Murphy SL, et al. Br J Haematol. 2008 Mar;140(5):479-87. doi: 10.1111/j.1365-2141.2007.06942.x. Br J Haematol. 2008. PMID: 18275425 Free PMC article. Review.

9

Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.

Mingozzi F, Chen Y, Murphy SL, Edmonson SC, Tai A, Price SD, Metzger ME, Zhou S, Wright JF, Donahue RE, Dunbar CE, High KA. Mingozzi F, et al. Among authors: murphy sl. Mol Ther. 2012 Jul;20(7):1410-6. doi: 10.1038/mt.2012.84. Epub 2012 May 8. Mol Ther. 2012. PMID: 22565846 Free PMC article.

10

In vivo genome editing restores haemostasis in a mouse model of haemophilia.

Li H, Haurigot V, Doyon Y, Li T, Wong SY, Bhagwat AS, Malani N, Anguela XM, Sharma R, Ivanciu L, Murphy SL, Finn JD, Khazi FR, Zhou S, Paschon DE, Rebar EJ, Bushman FD, Gregory PD, Holmes MC, High KA. Li H, et al. Among authors: murphy sl. Nature. 2011 Jun 26;475(7355):217-21. doi: 10.1038/nature10177. Nature. 2011. PMID: 21706032 Free PMC article.

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