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An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.
Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, Wagner G, Näär AM. Yang F, et al. Among authors: naar am. Nature. 2006 Aug 10;442(7103):700-4. doi: 10.1038/nature04942. Epub 2006 Jun 21. Nature. 2006. PMID: 16799563
A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM. Thakur JK, et al. Among authors: naar am. Nature. 2008 Apr 3;452(7187):604-9. doi: 10.1038/nature06836. Nature. 2008. PMID: 18385733
Structure of the VP16 transactivator target in the Mediator.
Milbradt AG, Kulkarni M, Yi T, Takeuchi K, Sun ZY, Luna RE, Selenko P, Näär AM, Wagner G. Milbradt AG, et al. Among authors: naar am. Nat Struct Mol Biol. 2011 Apr;18(4):410-5. doi: 10.1038/nsmb.1999. Epub 2011 Mar 6. Nat Struct Mol Biol. 2011. PMID: 21378963 Free PMC article.
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.
Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H. Nishikawa JL, et al. Among authors: naar am. Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17. Nature. 2016. PMID: 26886795 Free PMC article.
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM. Walker AK, et al. Among authors: naar am. Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210. Genes Dev. 2010. PMID: 20595232 Free PMC article.
60 results