Abbenante G - Search Results

1

Twists or turns: stabilising alpha vs. beta turns in tetrapeptides.

Hoang HN, Hill TA, Ruiz-Gómez G, Diness F, Mason JM, Wu C, Abbenante G, Shepherd NE, Fairlie DP. Hoang HN, et al. Among authors: abbenante g. Chem Sci. 2019 Oct 3;10(45):10595-10600. doi: 10.1039/c9sc04153b. eCollection 2019 Dec 7. Chem Sci. 2019. PMID: 32110345 Free PMC article.

2

Correction: Downsizing the BAD BH3 peptide to small constrained α-helices with improved ligand efficiency.

Shepherd NE, Harrison RS, Ruiz-Gomez G, Abbenante G, Mason JM, Fairlie DP. Shepherd NE, et al. Among authors: abbenante g. Org Biomol Chem. 2016 Dec 28;14(48):11525. doi: 10.1039/c6ob90178f. Epub 2016 Nov 23. Org Biomol Chem. 2016. PMID: 27879976

3

Downsizing the BAD BH3 peptide to small constrained α-helices with improved ligand efficiency.

Shepherd NE, Harrison RS, Ruiz-Gomez G, Abbenante G, Mason JM, Fairlie DP. Shepherd NE, et al. Among authors: abbenante g. Org Biomol Chem. 2016 Nov 22;14(46):10939-10945. doi: 10.1039/c6ob02185a. Org Biomol Chem. 2016. PMID: 27819377

4

New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

Pearson MS, Jariwala AR, Abbenante G, Plieskatt J, Wilson D, Bottazzi ME, Hotez PJ, Keegan B, Bethony JM, Loukas A. Pearson MS, et al. Among authors: abbenante g. Hum Vaccin Immunother. 2015;11(5):1251-7. doi: 10.4161/21645515.2014.980199. Hum Vaccin Immunother. 2015. PMID: 26018444 Free PMC article.

5

Protein α-turns recreated in structurally stable small molecules.

Hoang HN, Driver RW, Beyer RL, Malde AK, Le GT, Abbenante G, Mark AE, Fairlie DP. Hoang HN, et al. Among authors: abbenante g. Angew Chem Int Ed Engl. 2011 Nov 18;50(47):11107-11. doi: 10.1002/anie.201105119. Epub 2011 Sep 29. Angew Chem Int Ed Engl. 2011. PMID: 21956852 No abstract available.

6

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice.

Harrison RS, Ruiz-Gómez G, Hill TA, Chow SY, Shepherd NE, Lohman RJ, Abbenante G, Hoang HN, Fairlie DP. Harrison RS, et al. Among authors: abbenante g. J Med Chem. 2010 Dec 9;53(23):8400-8. doi: 10.1021/jm101139f. Epub 2010 Nov 10. J Med Chem. 2010. PMID: 21067234

7

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W. Abbenante G, et al. J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777. J Med Chem. 2010. PMID: 20684600

8

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency.

Harrison RS, Shepherd NE, Hoang HN, Ruiz-Gómez G, Hill TA, Driver RW, Desai VS, Young PR, Abbenante G, Fairlie DP. Harrison RS, et al. Among authors: abbenante g. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11686-91. doi: 10.1073/pnas.1002498107. Epub 2010 Jun 11. Proc Natl Acad Sci U S A. 2010. PMID: 20543141 Free PMC article.

9

Selective hexapeptide agonists and antagonists for human complement C3a receptor.

Scully CC, Blakeney JS, Singh R, Hoang HN, Abbenante G, Reid RC, Fairlie DP. Scully CC, et al. Among authors: abbenante g. J Med Chem. 2010 Jul 8;53(13):4938-48. doi: 10.1021/jm1003705. J Med Chem. 2010. PMID: 20527893

10

Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure.

Ruiz-Gómez G, Tyndall JD, Pfeiffer B, Abbenante G, Fairlie DP. Ruiz-Gómez G, et al. Among authors: abbenante g. Chem Rev. 2010 Apr 14;110(4):PR1-41. doi: 10.1021/cr900344w. Chem Rev. 2010. PMID: 20196554 Review. No abstract available.

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