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Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours.
McCormack AI, McDonald KL, Gill AJ, Clark SJ, Burt MG, Campbell KA, Braund WJ, Little NS, Cook RJ, Grossman AB, Robinson BG, Clifton-Bligh RJ. McCormack AI, et al. Among authors: little ns. Clin Endocrinol (Oxf). 2009 Aug;71(2):226-33. doi: 10.1111/j.1365-2265.2008.03487.x. Epub 2008 Dec 3. Clin Endocrinol (Oxf). 2009. PMID: 19067722
Wnt pathway inhibitors are strongly down-regulated in pituitary tumors.
Elston MS, Gill AJ, Conaglen JV, Clarkson A, Shaw JM, Law AJ, Cook RJ, Little NS, Clifton-Bligh RJ, Robinson BG, McDonald KL. Elston MS, et al. Among authors: little ns. Endocrinology. 2008 Mar;149(3):1235-42. doi: 10.1210/en.2007-0542. Epub 2007 Dec 13. Endocrinology. 2008. PMID: 18079202
Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival.
McDonald KL, McDonnell J, Muntoni A, Henson JD, Hegi ME, von Deimling A, Wheeler HR, Cook RJ, Biggs MT, Little NS, Robinson BG, Reddel RR, Royds JA. McDonald KL, et al. Among authors: little ns. J Neuropathol Exp Neurol. 2010 Jul;69(7):729-36. doi: 10.1097/NEN.0b013e3181e576cf. J Neuropathol Exp Neurol. 2010. PMID: 20535033
IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients.
McDonald KL, O'Sullivan MG, Parkinson JF, Shaw JM, Payne CA, Brewer JM, Young L, Reader DJ, Wheeler HT, Cook RJ, Biggs MT, Little NS, Teo C, Stone G, Robinson BG. McDonald KL, et al. Among authors: little ns. J Neuropathol Exp Neurol. 2007 May;66(5):405-17. doi: 10.1097/nen.0b013e31804567d7. J Neuropathol Exp Neurol. 2007. PMID: 17483698
62 results