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Practical synthesis of a p38 MAP kinase inhibitor.
Achmatowicz M, Thiel OR, Wheeler P, Bernard C, Huang J, Larsen RD, Faul MM. Achmatowicz M, et al. Among authors: thiel or. J Org Chem. 2009 Jan 16;74(2):795-809. doi: 10.1021/jo802186m. J Org Chem. 2009. PMID: 19086898
Practical synthesis of a vanilloid receptor-1 antagonist.
Thiel OR, Bernard C, King T, Dilmeghani-Seran M, Bostick T, Larsen RD, Faul MM. Thiel OR, et al. J Org Chem. 2008 May 2;73(9):3508-15. doi: 10.1021/jo8002216. Epub 2008 Mar 20. J Org Chem. 2008. PMID: 18351744
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production.
Achmatowicz MM, Allen JG, Bio MM, Bartberger MD, Borths CJ, Colyer JT, Crockett RD, Hwang TL, Koek JN, Osgood SA, Roberts SW, Swietlow A, Thiel OR, Caille S. Achmatowicz MM, et al. Among authors: thiel or. J Org Chem. 2016 Jun 3;81(11):4736-43. doi: 10.1021/acs.joc.6b00646. Epub 2016 May 20. J Org Chem. 2016. PMID: 27152753
Novel vanilloid receptor-1 antagonists: 3. The identification of a second-generation clinical candidate with improved physicochemical and pharmacokinetic properties.
Wang HL, Katon J, Balan C, Bannon AW, Bernard C, Doherty EM, Dominguez C, Gavva NR, Gore V, Ma V, Nishimura N, Surapaneni S, Tang P, Tamir R, Thiel O, Treanor JJ, Norman MH. Wang HL, et al. J Med Chem. 2007 Jul 26;50(15):3528-39. doi: 10.1021/jm070191h. Epub 2007 Jun 22. J Med Chem. 2007. PMID: 17585751
9,354 results