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Site-specific antibody-drug conjugation through glycoengineering.
Zhou Q, Stefano JE, Manning C, Kyazike J, Chen B, Gianolio DA, Park A, Busch M, Bird J, Zheng X, Simonds-Mannes H, Kim J, Gregory RC, Miller RJ, Brondyk WH, Dhal PK, Pan CQ. Zhou Q, et al. Among authors: park a. Bioconjug Chem. 2014 Mar 19;25(3):510-20. doi: 10.1021/bc400505q. Epub 2014 Feb 28. Bioconjug Chem. 2014. PMID: 24533768
Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues.
Zhou Q, Kyazike J, Boudanova E, Drzyzga M, Honey D, Cost R, Hou L, Duffieux F, Brun MP, Park A, Qiu H. Zhou Q, et al. Among authors: park a. Pharmaceuticals (Basel). 2021 Jul 14;14(7):672. doi: 10.3390/ph14070672. Pharmaceuticals (Basel). 2021. PMID: 34358098 Free PMC article.
Engineered Fc-glycosylation switch to eliminate antibody effector function.
Zhou Q, Jaworski J, Zhou Y, Valente D, Cotton J, Honey D, Boudanova E, Beninga J, Rao E, Wei R, Mauriac C, Pan C, Park A, Qiu H. Zhou Q, et al. Among authors: park a. MAbs. 2020 Jan-Dec;12(1):1814583. doi: 10.1080/19420862.2020.1814583. MAbs. 2020. PMID: 32892677 Free PMC article.
2,781 results