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Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.
Yuen DY, Dwyer RM, Matthews VB, Zhang L, Drew BG, Neill B, Kingwell BA, Clark MG, Rattigan S, Febbraio MA. Yuen DY, et al. Among authors: neill b. Diabetes. 2009 May;58(5):1086-95. doi: 10.2337/db08-0775. Epub 2009 Feb 2. Diabetes. 2009. PMID: 19188427 Free PMC article.
FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle.
Southgate RJ, Neill B, Prelovsek O, El-Osta A, Kamei Y, Miura S, Ezaki O, McLoughlin TJ, Zhang W, Unterman TG, Febbraio MA. Southgate RJ, et al. Among authors: neill b. J Biol Chem. 2007 Jul 20;282(29):21176-86. doi: 10.1074/jbc.M702039200. Epub 2007 May 17. J Biol Chem. 2007. Retraction in: J Biol Chem. 2009 Jul 24;284(30):20440. doi: 10.1074/jbc.a702039200. PMID: 17510058 Free article. Retracted.
Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
Kraakman MJ, Kammoun HL, Allen TL, Deswaerte V, Henstridge DC, Estevez E, Matthews VB, Neill B, White DA, Murphy AJ, Peijs L, Yang C, Risis S, Bruce CR, Du XJ, Bobik A, Lee-Young RS, Kingwell BA, Vasanthakumar A, Shi W, Kallies A, Lancaster GI, Rose-John S, Febbraio MA. Kraakman MJ, et al. Among authors: neill b. Cell Metab. 2015 Mar 3;21(3):403-16. doi: 10.1016/j.cmet.2015.02.006. Cell Metab. 2015. PMID: 25738456 Free article.
110 results