Bhat RA - Search Results

1

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation.

Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, Pitts K, Krishnamurthy G, Gopalsamy A, Shi M, Kern JC, Commons TJ, Woodworth RP, Wilson MA, Welmaker GS, Trybulski EJ, Moore WJ. Bodine PV, et al. Among authors: bhat ra. Bone. 2009 Jun;44(6):1063-8. doi: 10.1016/j.bone.2009.02.013. Epub 2009 Feb 27. Bone. 2009. PMID: 19254787

2

Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides.

Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitts K, Stauffer B, Trybulski EJ, Welmaker GS, Wilson M, Bodine PV. Moore WJ, et al. J Med Chem. 2009 Jan 8;52(1):105-16. doi: 10.1021/jm801144h. J Med Chem. 2009. PMID: 19072540

3

Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors.

Shi M, Stauffer B, Bhat R, Billiard J, Ponce-de-Leon H, Seestaller-Wehr L, Fukayama S, Mangine A, Moran R, Krishnamurthy G, Bodine P, Gopalsamy A. Shi M, et al. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6337-9. doi: 10.1016/j.bmcl.2009.09.085. Epub 2009 Sep 25. Bioorg Med Chem Lett. 2009. PMID: 19819694

4

Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II.

Moore WJ, Kern JC, Bhat R, Bodine PV, Fukyama S, Krishnamurthy G, Magolda RL, Pitts K, Stauffer B, Trybulski EJ. Moore WJ, et al. Bioorg Med Chem. 2010 Jan 1;18(1):190-201. doi: 10.1016/j.bmc.2009.11.002. Epub 2009 Nov 6. Bioorg Med Chem. 2010. PMID: 19932972

5

Regulated expression of sFRP-1 protein by the GeneSwitch system.

Bhat RA, Stauffer B, Komm BS, Bodine PV. Bhat RA, et al. Protein Expr Purif. 2004 Oct;37(2):327-35. doi: 10.1016/j.pep.2004.06.029. Protein Expr Purif. 2004. PMID: 15358354

6

The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis.

Bodine PV, Billiard J, Moran RA, Ponce-de-Leon H, McLarney S, Mangine A, Scrimo MJ, Bhat RA, Stauffer B, Green J, Stein GS, Lian JB, Komm BS. Bodine PV, et al. Among authors: bhat ra. J Cell Biochem. 2005 Dec 15;96(6):1212-30. doi: 10.1002/jcb.20599. J Cell Biochem. 2005. PMID: 16149051

7

The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation.

Liu Y, Bhat RA, Seestaller-Wehr LM, Fukayama S, Mangine A, Moran RA, Komm BS, Bodine PV, Billiard J. Liu Y, et al. Among authors: bhat ra. Mol Endocrinol. 2007 Feb;21(2):376-87. doi: 10.1210/me.2006-0342. Epub 2006 Nov 9. Mol Endocrinol. 2007. PMID: 17095577

8

Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.

Bhat RA, Stauffer B, Komm BS, Bodine PV. Bhat RA, et al. J Cell Biochem. 2007 Dec 15;102(6):1519-28. doi: 10.1002/jcb.21372. J Cell Biochem. 2007. PMID: 17471511

9

Wnt3-frizzled 1 chimera as a model to study canonical Wnt signaling.

Bhat RA, Stauffer B, Della Pietra A, Bodine PV. Bhat RA, et al. J Cell Biochem. 2010 Apr 1;109(5):876-84. doi: 10.1002/jcb.22447. J Cell Biochem. 2010. PMID: 20039315

10

Regulation of secreted Frizzled-related protein-1 by heparin.

Zhong X, Desilva T, Lin L, Bodine P, Bhat RA, Presman E, Pocas J, Stahl M, Kriz R. Zhong X, et al. Among authors: bhat ra. J Biol Chem. 2007 Jul 13;282(28):20523-33. doi: 10.1074/jbc.M609096200. Epub 2007 May 11. J Biol Chem. 2007. PMID: 17500071 Free article.

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