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A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation.
Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, Pitts K, Krishnamurthy G, Gopalsamy A, Shi M, Kern JC, Commons TJ, Woodworth RP, Wilson MA, Welmaker GS, Trybulski EJ, Moore WJ. Bodine PV, et al. Among authors: komm bs. Bone. 2009 Jun;44(6):1063-8. doi: 10.1016/j.bone.2009.02.013. Epub 2009 Feb 27. Bone. 2009. PMID: 19254787
Wnt signaling and osteoblastogenesis.
Bodine PV, Komm BS. Bodine PV, et al. Among authors: komm bs. Rev Endocr Metab Disord. 2006 Jun;7(1-2):33-9. doi: 10.1007/s11154-006-9002-4. Rev Endocr Metab Disord. 2006. PMID: 16960757 Review.
153 results