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Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models.
J Med Chem. 2009 Apr 9;52(7):1795-8. doi: 10.1021/jm801652d.
J Med Chem. 2009.
PMID: 19275170
Free PMC article.
Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine.
Edwankar RV, Edwankar CR, Deschamps J, Cook JM.
Edwankar RV, et al. Among authors: edwankar cr.
Org Lett. 2011 Oct 7;13(19):5216-9. doi: 10.1021/ol202101p. Epub 2011 Aug 30.
Org Lett. 2011.
PMID: 21877687
Free PMC article.
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Brønsted acid mediated cyclization of enaminones. Rapid and efficient access to the tetracyclic framework of the Strychnos alkaloids.
Edwankar RV, Edwankar CR, Namjoshi OA, Deschamps JR, Cook JM.
Edwankar RV, et al. Among authors: edwankar cr.
J Nat Prod. 2012 Feb 24;75(2):181-8. doi: 10.1021/np200759h. Epub 2012 Jan 18.
J Nat Prod. 2012.
PMID: 22257244
Free PMC article.
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Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids.
Edwankar CR, Edwankar RV, Deschamps JR, Cook JM.
Edwankar CR, et al.
Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11762-5. doi: 10.1002/anie.201206015. Epub 2012 Oct 16.
Angew Chem Int Ed Engl. 2012.
PMID: 23073985
Free PMC article.
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Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids.
Edwankar CR, Edwankar RV, Namjoshi OA, Liao X, Cook JM.
Edwankar CR, et al.
J Org Chem. 2013 Jul 5;78(13):6471-87. doi: 10.1021/jo400469t. Epub 2013 Jun 18.
J Org Chem. 2013.
PMID: 23721107
Free PMC article.
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General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine.
Edwankar RV, Edwankar CR, Deschamps JR, Cook JM.
Edwankar RV, et al. Among authors: edwankar cr.
J Org Chem. 2014 Nov 7;79(21):10030-48. doi: 10.1021/jo5016163. Epub 2014 Oct 15.
J Org Chem. 2014.
PMID: 25247616
Free PMC article.
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Recent progress in the total synthesis of indole alkaloids.
Edwankar CR, Edwankar RV, Namjoshi OA, Rallapalli SK, Yang J, Cook JM.
Edwankar CR, et al.
Curr Opin Drug Discov Devel. 2009 Nov;12(6):752-71.
Curr Opin Drug Discov Devel. 2009.
PMID: 19894188
Review.
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