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CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes.
Reindl C, Quentmeier H, Petropoulos K, Greif PA, Benthaus T, Argiropoulos B, Mellert G, Vempati S, Duyster J, Buske C, Bohlander SK, Humphries KR, Hiddemann W, Spiekermann K. Reindl C, et al. Among authors: quentmeier h. Clin Cancer Res. 2009 Apr 1;15(7):2238-47. doi: 10.1158/1078-0432.CCR-08-1325. Epub 2009 Mar 10. Clin Cancer Res. 2009. PMID: 19276253
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
Stief SM, Hanneforth AL, Weser S, Mattes R, Carlet M, Liu WH, Bartoschek MD, Domínguez Moreno H, Oettle M, Kempf J, Vick B, Ksienzyk B, Tizazu B, Rothenberg-Thurley M, Quentmeier H, Hiddemann W, Vosberg S, Greif PA, Metzeler KH, Schotta G, Bultmann S, Jeremias I, Leonhardt H, Spiekermann K. Stief SM, et al. Among authors: quentmeier h. Leukemia. 2020 Jan;34(1):50-62. doi: 10.1038/s41375-019-0497-6. Epub 2019 Jun 14. Leukemia. 2020. PMID: 31201358 Free PMC article.
FLT3: receptor and ligand.
Drexler HG, Quentmeier H. Drexler HG, et al. Among authors: quentmeier h. Growth Factors. 2004 Jun;22(2):71-3. doi: 10.1080/08977190410001700989. Growth Factors. 2004. PMID: 15253381 Review.
Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party.
Virappane P, Gale R, Hills R, Kakkas I, Summers K, Stevens J, Allen C, Green C, Quentmeier H, Drexler H, Burnett A, Linch D, Bonnet D, Lister TA, Fitzgibbon J. Virappane P, et al. Among authors: quentmeier h. J Clin Oncol. 2008 Nov 20;26(33):5429-35. doi: 10.1200/JCO.2008.16.0333. Epub 2008 Jun 30. J Clin Oncol. 2008. PMID: 18591546
112 results