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Structure of granzyme C reveals an unusual mechanism of protease autoinhibition.
Kaiserman D, Buckle AM, Van Damme P, Irving JA, Law RH, Matthews AY, Bashtannyk-Puhalovich T, Langendorf C, Thompson P, Vandekerckhove J, Gevaert K, Whisstock JC, Bird PI. Kaiserman D, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5587-92. doi: 10.1073/pnas.0811968106. Epub 2009 Mar 19. Proc Natl Acad Sci U S A. 2009. PMID: 19299505 Free PMC article.
Serpins in the Caenorhabditis elegans genome.
Whisstock JC, Irving JA, Bottomley SP, Pike RN, Lesk AM. Whisstock JC, et al. Proteins. 1999 Jul 1;36(1):31-41. doi: 10.1002/(sici)1097-0134(19990701)36:1<31::aid-prot3>3.3.co;2-h. Proteins. 1999. PMID: 10373004
Protein structural alignments and functional genomics.
Irving JA, Whisstock JC, Lesk AM. Irving JA, et al. Among authors: whisstock jc. Proteins. 2001 Feb 15;42(3):378-82. doi: 10.1002/1097-0134(20010215)42:3<378::aid-prot70>3.0.co;2-3. Proteins. 2001. PMID: 11151008
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature.
Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O'Donnell E, Salvesen GS, Travis J, Whisstock JC. Silverman GA, et al. Among authors: whisstock jc. J Biol Chem. 2001 Sep 7;276(36):33293-6. doi: 10.1074/jbc.R100016200. Epub 2001 Jul 2. J Biol Chem. 2001. PMID: 11435447 Free article. Review. No abstract available.
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity.
Nandurkar HH, Caldwell KK, Whisstock JC, Layton MJ, Gaudet EA, Norris FA, Majerus PW, Mitchell CA. Nandurkar HH, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9499-504. doi: 10.1073/pnas.171306098. Proc Natl Acad Sci U S A. 2001. PMID: 11504939 Free PMC article.
270 results