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Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
van Eijk M, Aten J, Bijl N, Ottenhoff R, van Roomen CP, Dubbelhuis PF, Seeman I, Ghauharali-van der Vlugt K, Overkleeft HS, Arbeeny C, Groen AK, Aerts JM. van Eijk M, et al. Among authors: arbeeny c. PLoS One. 2009;4(3):e4723. doi: 10.1371/journal.pone.0004723. Epub 2009 Mar 23. PLoS One. 2009. PMID: 19305508 Free PMC article.
The Novel Phosphate and Bile Acid Sequestrant Polymer SAR442357 Delays Disease Progression in a Rat Model of Diabetic Nephropathy.
Castañeda TR, Méndez M, Davison I, Elvert R, Schwahn U, Boldina G, Rocher C, Scherer P, Singh K, Bangari DS, Falkenhahn M, Kannt A, Konkar A, Larsen PJ, Arbeeny C, Dhal PK, Hübschle T. Castañeda TR, et al. Among authors: arbeeny c. J Pharmacol Exp Ther. 2021 Feb;376(2):190-203. doi: 10.1124/jpet.120.000285. Epub 2020 Nov 17. J Pharmacol Exp Ther. 2021. PMID: 33203659
Npt2b deletion attenuates hyperphosphatemia associated with CKD.
Schiavi SC, Tang W, Bracken C, O'Brien SP, Song W, Boulanger J, Ryan S, Phillips L, Liu S, Arbeeny C, Ledbetter S, Sabbagh Y. Schiavi SC, et al. Among authors: arbeeny c. J Am Soc Nephrol. 2012 Oct;23(10):1691-700. doi: 10.1681/ASN.2011121213. Epub 2012 Aug 2. J Am Soc Nephrol. 2012. PMID: 22859851 Free PMC article.
Intestinal npt2b plays a major role in phosphate absorption and homeostasis.
Sabbagh Y, O'Brien SP, Song W, Boulanger JH, Stockmann A, Arbeeny C, Schiavi SC. Sabbagh Y, et al. Among authors: arbeeny c. J Am Soc Nephrol. 2009 Nov;20(11):2348-58. doi: 10.1681/ASN.2009050559. Epub 2009 Sep 3. J Am Soc Nephrol. 2009. PMID: 19729436 Free PMC article.
42 results