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Single nucleotide polymorphisms that cause structural changes in the cyclic AMP receptor protein transcriptional regulator of the tuberculosis vaccine strain Mycobacterium bovis BCG alter global gene expression without attenuating growth.
Hunt DM, Saldanha JW, Brennan JF, Benjamin P, Strom M, Cole JA, Spreadbury CL, Buxton RS. Hunt DM, et al. Infect Immun. 2008 May;76(5):2227-34. doi: 10.1128/IAI.01410-07. Epub 2008 Mar 10. Infect Immun. 2008. PMID: 18332206 Free PMC article.
A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor.
Rickman L, Scott C, Hunt DM, Hutchinson T, Menéndez MC, Whalan R, Hinds J, Colston MJ, Green J, Buxton RS. Rickman L, et al. Among authors: hunt dm. Mol Microbiol. 2005 Jun;56(5):1274-86. doi: 10.1111/j.1365-2958.2005.04609.x. Mol Microbiol. 2005. PMID: 15882420 Free PMC article.
346 results