Nemeth G - Search Results

1

8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists.

Gilligan PJ, He L, Clarke T, Tivitmahaisoon P, Lelas S, Li YW, Heman K, Fitzgerald L, Miller K, Zhang G, Marshall A, Krause C, McElroy J, Ward K, Shen H, Wong H, Grossman S, Nemeth G, Zaczek R, Arneric SP, Hartig P, Robertson DW, Trainor G. Gilligan PJ, et al. Among authors: nemeth g. J Med Chem. 2009 May 14;52(9):3073-83. doi: 10.1021/jm9000242. J Med Chem. 2009. PMID: 19361210

2

Corticotropin-releasing hormone receptor antagonists: framework design and synthesis guided by ligand conformational studies.

Hodge CN, Aldrich PE, Wasserman ZR, Fernandez CH, Nemeth GA, Arvanitis A, Cheeseman RS, Chorvat RJ, Ciganek E, Christos TE, Gilligan PJ, Krenitsky P, Scholfield E, Strucely P. Hodge CN, et al. Among authors: nemeth ga. J Med Chem. 1999 Mar 11;42(5):819-32. doi: 10.1021/jm980223o. J Med Chem. 1999. PMID: 10072680

3

NMR characterization of a novel bile acid sequestrant, DMP 504.

Lerke SA, Nemeth G, Schubert E, Hovsepian PK. Lerke SA, et al. Among authors: nemeth g. J Pharm Biomed Anal. 2001 Feb;24(4):681-7. doi: 10.1016/s0731-7085(00)00470-2. J Pharm Biomed Anal. 2001. PMID: 11272326

4

Solubility enhancement of a bisnaphthalimide tumoricidal agent, DMP 840, through complexation.

Raghavan KS, Nemeth GA, Gray DB, Hussain MA. Raghavan KS, et al. Among authors: nemeth ga. Pharm Dev Technol. 1996 Oct;1(3):231-8. doi: 10.3109/10837459609022591. Pharm Dev Technol. 1996. PMID: 9552305

5

Liquid chromatography/mass spectrometry and high-field nuclear magnetic resonance characterization of novel mixed diconjugates of the non-nucleoside human immunodeficiency virus-1 reverse transcriptase inhibitor, efavirenz.

Mutlib AE, Chen H, Nemeth G, Gan LS, Christ DD. Mutlib AE, et al. Among authors: nemeth g. Drug Metab Dispos. 1999 Sep;27(9):1045-56. Drug Metab Dispos. 1999. PMID: 10460805

6

Characterization of novel glutathione adducts of a non-nucleoside reverse transcriptase inhibitor, (S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3, 4-dihydro-2(1H)-quinazolinone (DPC 961), in rats. Possible formation of an oxirene metabolic intermediate from a disubstituted alkyne.

Mutlib A, Chen H, Shockcor J, Espina R, Chen S, Cao K, Du A, Nemeth G, Prakash S, Gan LS. Mutlib A, et al. Among authors: nemeth g. Chem Res Toxicol. 2000 Aug;13(8):775-84. doi: 10.1021/tx000029g. Chem Res Toxicol. 2000. PMID: 10956066

7

Mass spectrometric and NMR characterization of metabolites of roxifiban, a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor.

Mutlib AE, Diamond S, Shockcor J, Way R, Nemeth G, Gan L, Christ DD. Mutlib AE, et al. Among authors: nemeth g. Xenobiotica. 2000 Nov;30(11):1091-110. doi: 10.1080/00498250010006591. Xenobiotica. 2000. PMID: 11197070

8

Degradation kinetics of DMP 777, an elastase inhibitor.

Raghavan KS, Gray DB, Scholz TH, Nemeth GA, Hussain MA. Raghavan KS, et al. Among authors: nemeth ga. Pharm Res. 1996 Dec;13(12):1815-20. doi: 10.1023/a:1016076907072. Pharm Res. 1996. PMID: 8987077

9

A spectroscopic investigation of DuP 747 polymorphs.

Raghavan K, Dwivedi A, Campbell GC Jr, Nemeth G, Hussain MA. Raghavan K, et al. Among authors: nemeth g. J Pharm Biomed Anal. 1994 Jun;12(6):777-85. doi: 10.1016/0731-7085(94)e0002-i. J Pharm Biomed Anal. 1994. PMID: 7918780

10

Identification and characterization of efavirenz metabolites by liquid chromatography/mass spectrometry and high field NMR: species differences in the metabolism of efavirenz.

Mutlib AE, Chen H, Nemeth GA, Markwalder JA, Seitz SP, Gan LS, Christ DD. Mutlib AE, et al. Among authors: nemeth ga. Drug Metab Dispos. 1999 Nov;27(11):1319-33. Drug Metab Dispos. 1999. PMID: 10534318

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