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Page 1
Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13.
Monovich LG, Tommasi RA, Fujimoto RA, Blancuzzi V, Clark K, Cornell WD, Doti R, Doughty J, Fang J, Farley D, Fitt J, Ganu V, Goldberg R, Goldstein R, Lavoie S, Kulathila R, Macchia W, Parker DT, Melton R, O'Byrne E, Pastor G, Pellas T, Quadros E, Reel N, Roland DM, Sakane Y, Singh H, Skiles J, Somers J, Toscano K, Wigg A, Zhou S, Zhu L, Shieh WC, Xue S, McQuire LW. Monovich LG, et al. Among authors: fitt j. J Med Chem. 2009 Jun 11;52(11):3523-38. doi: 10.1021/jm801394m. J Med Chem. 2009. PMID: 19422229
Identification of dipeptidyl nitriles as potent and selective inhibitors of cathepsin B through structure-based drug design.
Greenspan PD, Clark KL, Tommasi RA, Cowen SD, McQuire LW, Farley DL, van Duzer JH, Goldberg RL, Zhou H, Du Z, Fitt JJ, Coppa DE, Fang Z, Macchia W, Zhu L, Capparelli MP, Goldstein R, Wigg AM, Doughty JR, Bohacek RS, Knap AK. Greenspan PD, et al. Among authors: fitt jj. J Med Chem. 2001 Dec 20;44(26):4524-34. doi: 10.1021/jm010206q. J Med Chem. 2001. PMID: 11741472
Total synthesis of dl-9-deoxyprostaglandin E1.
Finch N, Fitt JJ, Hsu IH. Finch N, et al. Among authors: fitt jj. J Org Chem. 1975 Jan 24;40(2):206-15. doi: 10.1021/jo00890a012. J Org Chem. 1975. PMID: 1133615 No abstract available.
Total synthesis of dl-prostaglandin E1.
Finch N, Vecchia LD, Fitt JJ, Stephani R, Vlattas I. Finch N, et al. Among authors: fitt jj. J Org Chem. 1973 Dec 28;38(26):4412-24. doi: 10.1021/jo00965a014. J Org Chem. 1973. PMID: 4782677 No abstract available.
Cyclopentenone synthesis by directed cyclization.
Finch N, Fitt JJ, Hsu IH. Finch N, et al. Among authors: fitt jj. J Org Chem. 1971 Oct 22;36(21):3191-6. doi: 10.1021/jo00820a025. J Org Chem. 1971. PMID: 5134353 No abstract available.
12 results