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Striatum is more vulnerable to oxidative damage induced by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency as compared to liver.
Int J Dev Neurosci. 2009 Jun;27(4):351-6. doi: 10.1016/j.ijdevneu.2009.03.001. Epub 2009 Mar 13.
Int J Dev Neurosci. 2009.
PMID: 19460629
Glycine provokes lipid oxidative damage and reduces the antioxidant defenses in brain cortex of young rats.
Leipnitz G, Solano AF, Seminotti B, Amaral AU, Fernandes CG, Beskow AP, Dutra Filho CS, Wajner M.
Leipnitz G, et al. Among authors: beskow ap.
Cell Mol Neurobiol. 2009 Mar;29(2):253-61. doi: 10.1007/s10571-008-9318-6. Epub 2008 Oct 2.
Cell Mol Neurobiol. 2009.
PMID: 18830815
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D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats.
da Silva Lde B, Leipnitz G, Seminotti B, Fernandes CG, Beskow AP, Amaral AU, Wajner M.
da Silva Lde B, et al. Among authors: beskow ap.
Brain Res. 2009 Feb 23;1256:34-42. doi: 10.1016/j.brainres.2008.12.036. Epub 2008 Dec 24.
Brain Res. 2009.
PMID: 19133242
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Influence of ketone bodies on oxidative stress parameters in brain of developing rats in vitro.
Beskow AP, Fernandes CG, Leipnitz G, da Silva Lde B, Seminotti B, Amaral AU, Wyse AT, Wannmacher CM, Vargas CR, Dutra-Filho CS, Wajner M.
Beskow AP, et al.
Metab Brain Dis. 2008 Dec;23(4):411-25. doi: 10.1007/s11011-008-9108-3. Epub 2008 Sep 6.
Metab Brain Dis. 2008.
PMID: 18777091
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