Kobilka B - Search Results

1

The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex.

Yao XJ, Vélez Ruiz G, Whorton MR, Rasmussen SG, DeVree BT, Deupi X, Sunahara RK, Kobilka B. Yao XJ, et al. Among authors: kobilka b. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9501-6. doi: 10.1073/pnas.0811437106. Epub 2009 May 22. Proc Natl Acad Sci U S A. 2009. PMID: 19470481 Free PMC article.

2

Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.

Rohrer DK, Desai KH, Jasper JR, Stevens ME, Regula DP Jr, Barsh GS, Bernstein D, Kobilka BK. Rohrer DK, et al. Among authors: kobilka bk. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7375-80. doi: 10.1073/pnas.93.14.7375. Proc Natl Acad Sci U S A. 1996. PMID: 8693001 Free PMC article.

3

Examination of ligand-induced conformational changes in the beta2 adrenergic receptor.

Kobilka B, Gether U, Seifert R, Lin S, Ghanouni P. Kobilka B, et al. Life Sci. 1998;62(17-18):1509-12. doi: 10.1016/s0024-3205(98)00098-8. Life Sci. 1998. PMID: 9585127 Review.

4

Characterization of ligand-induced conformational states in the beta 2 adrenergic receptor.

Kobilka B, Gether U, Seifert R, Lin S, Ghanouni P. Kobilka B, et al. J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):293-300. doi: 10.3109/10799899909036652. J Recept Signal Transduct Res. 1999. PMID: 10071765

5

The effect of pH on beta(2) adrenoceptor function. Evidence for protonation-dependent activation.

Ghanouni P, Schambye H, Seifert R, Lee TW, Rasmussen SG, Gether U, Kobilka BK. Ghanouni P, et al. Among authors: kobilka bk. J Biol Chem. 2000 Feb 4;275(5):3121-7. doi: 10.1074/jbc.275.5.3121. J Biol Chem. 2000. PMID: 10652295 Free article.

6

Allosteric activation of the CaR by L-amino acids.

Kobilka B. Kobilka B. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4419-20. doi: 10.1073/pnas.97.9.4419. Proc Natl Acad Sci U S A. 2000. PMID: 10781033 Free PMC article. Review. No abstract available.

7

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor.

Ghanouni P, Gryczynski Z, Steenhuis JJ, Lee TW, Farrens DL, Lakowicz JR, Kobilka BK. Ghanouni P, et al. Among authors: kobilka bk. J Biol Chem. 2001 Jul 6;276(27):24433-6. doi: 10.1074/jbc.C100162200. Epub 2001 Apr 24. J Biol Chem. 2001. PMID: 11320077 Free article.

8

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor.

Ghanouni P, Steenhuis JJ, Farrens DL, Kobilka BK. Ghanouni P, et al. Among authors: kobilka bk. Proc Natl Acad Sci U S A. 2001 May 22;98(11):5997-6002. doi: 10.1073/pnas.101126198. Epub 2001 May 15. Proc Natl Acad Sci U S A. 2001. PMID: 11353823 Free PMC article.

9

Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations.

Seifert R, Wenzel-Seifert K, Gether U, Kobilka BK. Seifert R, et al. Among authors: kobilka bk. J Pharmacol Exp Ther. 2001 Jun;297(3):1218-26. J Pharmacol Exp Ther. 2001. PMID: 11356949

10

Single-molecule spectroscopy of the beta(2) adrenergic receptor: observation of conformational substates in a membrane protein.

Peleg G, Ghanouni P, Kobilka BK, Zare RN. Peleg G, et al. Among authors: kobilka bk. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8469-74. doi: 10.1073/pnas.151239698. Epub 2001 Jul 3. Proc Natl Acad Sci U S A. 2001. PMID: 11438704 Free PMC article.

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