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Minimally invasive colon resection for malignant colonic conditions is associated with a transient early increase in plasma sVEGFR1 and a decrease in sVEGFR2 levels after surgery.
Shantha Kumara HM, Cabot JC, Hoffman A, Luchtefeld M, Kalady MF, Hyman N, Feingold D, Baxter R, Whelan RL. Shantha Kumara HM, et al. Among authors: feingold d. Surg Endosc. 2010 Feb;24(2):283-9. doi: 10.1007/s00464-009-0575-3. Epub 2009 Jun 24. Surg Endosc. 2010. PMID: 19551437
Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2).
Shantha Kumara HM, Grieco MJ, Yan X, Kalady MF, DiMaggio V, Kim DG, Hyman N, Feingold DL, Whelan RL. Shantha Kumara HM, et al. Surg Endosc. 2010 Oct;24(10):2581-7. doi: 10.1007/s00464-010-1008-z. Epub 2010 Mar 31. Surg Endosc. 2010. PMID: 20354881
Perioperative sargramostim (recombinant human GM-CSF) induces an increase in the level of soluble VEGFR1 in colon cancer patients undergoing minimally invasive surgery.
Kirman I, Belizon A, Balik E, Feingold D, Arnell T, Horst P, Kumara S, Cekic V, Jain S, Nasar A, Whelan RL. Kirman I, et al. Among authors: feingold d. Eur J Surg Oncol. 2007 Dec;33(10):1169-76. doi: 10.1016/j.ejso.2007.03.014. Epub 2007 May 18. Eur J Surg Oncol. 2007. PMID: 17512160 Clinical Trial.
Colorectal resection, both open and laparoscopic-assisted, in patients with benign indications is associated with proangiogenic changes in plasma angiopoietin 1 and 2 levels.
Shantha Kumara HM, Hoffman A, Kim IY, Feingold D, Dujovny N, Kalady M, Luchtefeld M, Whelan RL. Shantha Kumara HM, et al. Among authors: feingold d. Surg Endosc. 2009 Feb;23(2):409-15. doi: 10.1007/s00464-008-0132-5. Epub 2008 Sep 24. Surg Endosc. 2009. PMID: 18813991 Clinical Trial.
328 results