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Synthesis of bicyclo[5.3.0]azulene derivatives.
Nolting DD, Nickels M, Price R, Gore JC, Pham W. Nolting DD, et al. Among authors: nickels m. Nat Protoc. 2009;4(8):1113-7. doi: 10.1038/nprot.2009.99. Epub 2009 Jul 9. Nat Protoc. 2009. PMID: 19617883 Free PMC article.
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Among authors: nickels ml. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.
Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.
Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.
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