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Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide).
Prat M, Fernández D, Buil MA, Crespo MI, Casals G, Ferrer M, Tort L, Castro J, Monleón JM, Gavaldà A, Miralpeix M, Ramos I, Doménech T, Vilella D, Antón F, Huerta JM, Espinosa S, López M, Sentellas S, González M, Albertí J, Segarra V, Cárdenas A, Beleta J, Ryder H. Prat M, et al. Among authors: tort l. J Med Chem. 2009 Aug 27;52(16):5076-92. doi: 10.1021/jm900132z. J Med Chem. 2009. PMID: 19653626
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists.
Prat M, Buil MA, Fernández MD, Castro J, Monleón JM, Tort L, Casals G, Ferrer M, Huerta JM, Espinosa S, López M, Segarra V, Gavaldà A, Miralpeix M, Ramos I, Vilella D, González M, Córdoba M, Cárdenas A, Antón F, Beleta J, Ryder H. Prat M, et al. Among authors: tort l. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3457-61. doi: 10.1016/j.bmcl.2011.03.096. Epub 2011 Apr 3. Bioorg Med Chem Lett. 2011. PMID: 21524581
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides as potent and long acting muscarinic antagonists.
Prat M, Buil MA, Fernández MD, Tort L, Monleón JM, Casals G, Ferrer M, Castro J, Gavaldà A, Miralpeix M, Ramos I, Vilella D, Huerta JM, Espinosa S, Hernández B, Segarra V, Córdoba M. Prat M, et al. Among authors: tort l. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1736-1741. doi: 10.1016/j.bmcl.2015.02.065. Epub 2015 Mar 5. Bioorg Med Chem Lett. 2015. PMID: 25800115
Homologous equivalence study of immunogenicity after third dose of Covid-19 vaccine (recombinant) with an interval of six months after the second dose, comparing the interval of eight and 12 weeks between the first two doses.
Vianna CM, da Silva E Sá GR, Seid MVH, Camacho LAB, Xavier JR, da Gama VC, de Castro TDM, Dos Santos EAP, de Almeida CD, Cruz RLS, Siqueira M, Maia MLS, Ferroco CLV, de Araújo MF, Tort LFL, Caetano BC. Vianna CM, et al. Among authors: tort lfl. Mem Inst Oswaldo Cruz. 2024 Sep 9;119:e240094. doi: 10.1590/0074-02760240094. eCollection 2024. Mem Inst Oswaldo Cruz. 2024. PMID: 39258623 Free PMC article. Clinical Trial.
Sea water acclimation of rainbow trout (Oncorhynchus mykiss) modulates the mucosal transcript immune response induced by Vibrio anguillarum and Aeromonas salmonicida vaccine, and prevents further transcription of stress-immune genes in response to acute stress.
Khansari AR, Wallbom N, Sundh H, Sandblom E, Tort L, Jönsson E. Khansari AR, et al. Among authors: tort l. Fish Shellfish Immunol. 2024 Sep;152:109733. doi: 10.1016/j.fsi.2024.109733. Epub 2024 Jun 27. Fish Shellfish Immunol. 2024. PMID: 38944251 Free article.
Transcriptional Evaluation of Neuropeptides, Hormones, and Tissue Repair Modulators in the Skin of Gilthead Sea Bream (Sparus aurata L.) Subjected to Mechanical Damage.
Piñera-Moreno R, Reyes-López FE, Goldstein M, Santillán-Araneda MJ, Robles-Planells B, Arancibia-Carvallo C, Vallejos-Vidal E, Cuesta A, Esteban MÁ, Tort L. Piñera-Moreno R, et al. Among authors: tort l. Animals (Basel). 2024 Jun 18;14(12):1815. doi: 10.3390/ani14121815. Animals (Basel). 2024. PMID: 38929434 Free PMC article.
179 results