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Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.
Forristal CE, Brown AL, Helwani FM, Winkler IG, Nowlan B, Barbier V, Powell RJ, Engler GA, Diakiw SM, Zannettino AC, Martin S, Pattabiraman D, D'Andrea RJ, Lewis ID, Levesque JP. Forristal CE, et al. Leukemia. 2015 Oct;29(10):2075-85. doi: 10.1038/leu.2015.102. Epub 2015 Apr 29. Leukemia. 2015. PMID: 25921247
Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80(+)VCAM1(+)CD169(+)ER-HR3(+)Ly6G(+) erythroid island macrophages in the mouse.
Jacobsen RN, Forristal CE, Raggatt LJ, Nowlan B, Barbier V, Kaur S, van Rooijen N, Winkler IG, Pettit AR, Levesque JP. Jacobsen RN, et al. Among authors: forristal ce. Exp Hematol. 2014 Jul;42(7):547-61.e4. doi: 10.1016/j.exphem.2014.03.009. Epub 2014 Apr 8. Exp Hematol. 2014. PMID: 24721610 Free article.
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