Wu H - Search Results

1

Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells.

Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL. Ilan Y, et al. Among authors: wu h. J Clin Immunol. 2010 Jan;30(1):167-77. doi: 10.1007/s10875-009-9323-7. Epub 2009 Sep 16. J Clin Immunol. 2010. PMID: 19756989 Free PMC article. Clinical Trial.

2

New immunosuppressive approaches: oral administration of CD3-specific antibody to treat autoimmunity.

Ochi H, Abraham M, Ishikawa H, Frenkel D, Yang K, Basso A, Wu H, Chen ML, Gandhi R, Miller A, Maron R, Weiner HL. Ochi H, et al. Among authors: wu h. J Neurol Sci. 2008 Nov 15;274(1-2):9-12. doi: 10.1016/j.jns.2008.07.027. Epub 2008 Sep 18. J Neurol Sci. 2008. PMID: 18804221 Free PMC article. Review.

3

Oral tolerance.

Weiner HL, da Cunha AP, Quintana F, Wu H. Weiner HL, et al. Among authors: wu h. Immunol Rev. 2011 May;241(1):241-59. doi: 10.1111/j.1600-065X.2011.01017.x. Immunol Rev. 2011. PMID: 21488901 Free PMC article. Review.

4

Oral tolerance.

Wu HY, Weiner HL. Wu HY, et al. Immunol Res. 2003;28(3):265-84. doi: 10.1385/IR:28:3:265. Immunol Res. 2003. PMID: 14713719 Review.

5

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.

Wu HY, Quintana FJ, Weiner HL. Wu HY, et al. J Immunol. 2008 Nov 1;181(9):6038-50. doi: 10.4049/jimmunol.181.9.6038. J Immunol. 2008. PMID: 18941193 Free PMC article.

6

Mucosal anti-CD3 monoclonal antibody attenuates collagen-induced arthritis that is associated with induction of LAP+ regulatory T cells and is enhanced by administration of an emulsome-based Th2-skewing adjuvant.

Wu HY, Maron R, Tukpah AM, Weiner HL. Wu HY, et al. J Immunol. 2010 Sep 15;185(6):3401-7. doi: 10.4049/jimmunol.1000836. Epub 2010 Aug 18. J Immunol. 2010. PMID: 20720210 Free PMC article.

7

In vivo anti-LAP mAb enhances IL-17/IFN-γ responses and abrogates anti-CD3-induced oral tolerance.

da Cunha AP, Wu HY, Rezende RM, Vandeventer T, Weiner HL. da Cunha AP, et al. Int Immunol. 2015 Feb;27(2):73-82. doi: 10.1093/intimm/dxu083. Epub 2014 Sep 6. Int Immunol. 2015. PMID: 25194146 Free PMC article.

8

Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

Ochi H, Abraham M, Ishikawa H, Frenkel D, Yang K, Basso AS, Wu H, Chen ML, Gandhi R, Miller A, Maron R, Weiner HL. Ochi H, et al. Among authors: wu h. Nat Med. 2006 Jun;12(6):627-35. doi: 10.1038/nm1408. Epub 2006 May 21. Nat Med. 2006. PMID: 16715091

9

Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells.

Wu HY, Center EM, Tsokos GC, Weiner HL. Wu HY, et al. Lupus. 2009 Jun;18(7):586-96. doi: 10.1177/0961203308100511. Lupus. 2009. PMID: 19433458 Free PMC article.

10

The mechanism of nasal tolerance in lupus prone mice is T-cell anergy induced by immature B cells that lack B7 expression.

Wu HY, Monsonego A, Weiner HL. Wu HY, et al. J Autoimmun. 2006 Mar;26(2):116-26. doi: 10.1016/j.jaut.2005.11.005. Epub 2006 Jan 19. J Autoimmun. 2006. PMID: 16426816

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