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Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
J Med Chem. 2009 Oct 22;52(20):6201-4. doi: 10.1021/jm900951n.
J Med Chem. 2009.
PMID: 19785435
Improved glycemic control in mice lacking Sglt1 and Sglt2.
Powell DR, DaCosta CM, Gay J, Ding ZM, Smith M, Greer J, Doree D, Jeter-Jones S, Mseeh F, Rodriguez LA, Harris A, Buhring L, Platt KA, Vogel P, Brommage R, Shadoan MK, Sands AT, Zambrowicz B.
Powell DR, et al.
Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E117-30. doi: 10.1152/ajpendo.00439.2012. Epub 2012 Nov 13.
Am J Physiol Endocrinol Metab. 2013.
PMID: 23149623
Free article.
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Effect of LX4211 on glucose homeostasis and body composition in preclinical models.
Powell DR, DaCosta CM, Smith M, Doree D, Harris A, Buhring L, Heydorn W, Nouraldeen A, Xiong W, Yalamanchili P, Mseeh F, Wilson A, Shadoan M, Zambrowicz B, Ding ZM.
Powell DR, et al.
J Pharmacol Exp Ther. 2014 Aug;350(2):232-42. doi: 10.1124/jpet.114.214304. Epub 2014 May 21.
J Pharmacol Exp Ther. 2014.
PMID: 24849925
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Mice Lacking Gpr75 are Hypophagic and Thin.
Powell DR, Doree DD, DaCosta CM, Platt KA, Brommage R, Buhring L, Revelli JP, Shadoan MK.
Powell DR, et al.
Diabetes Metab Syndr Obes. 2022 Jan 5;15:45-58. doi: 10.2147/DMSO.S342799. eCollection 2022.
Diabetes Metab Syndr Obes. 2022.
PMID: 35023939
Free PMC article.
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Pathology of congenital generalized lipodystrophy in Agpat2-/- mice.
Vogel P, Read R, Hansen G, Wingert J, Dacosta CM, Buhring LM, Shadoan M.
Vogel P, et al. Among authors: buhring lm.
Vet Pathol. 2011 May;48(3):642-54. doi: 10.1177/0300985810383870. Epub 2010 Nov 4.
Vet Pathol. 2011.
PMID: 21051554
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