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Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
Sarrazin N, Chavret-Reculon E, Bachelin C, Felfli M, Arab R, Gilardeau S, Brazhnikova E, Dubus E, Yaha-Cherif L, Lorenceau J, Picaud S, Rosolen S, Moissonnier P, Pouget P, Baron-Van Evercooren A. Sarrazin N, et al. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2115973119. doi: 10.1073/pnas.2115973119. Epub 2022 Mar 2. Proc Natl Acad Sci U S A. 2022. PMID: 35235463 Free PMC article.
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D, Delarasse C; NeuroCEB Brain Bank. Carvalho K, et al. Among authors: sarrazin n. Prog Neurobiol. 2021 Nov;206:102139. doi: 10.1016/j.pneurobio.2021.102139. Epub 2021 Aug 12. Prog Neurobiol. 2021. PMID: 34391810 Free article.
Adaptive human immunity drives remyelination in a mouse model of demyelination.
El Behi M, Sanson C, Bachelin C, Guillot-Noël L, Fransson J, Stankoff B, Maillart E, Sarrazin N, Guillemot V, Abdi H, Cournu-Rebeix I, Fontaine B, Zujovic V. El Behi M, et al. Among authors: sarrazin n. Brain. 2017 Apr 1;140(4):967-980. doi: 10.1093/brain/awx008. Brain. 2017. PMID: 28334918 Free PMC article.
A mouse model of Schwartz-Jampel syndrome reveals myelinating Schwann cell dysfunction with persistent axonal depolarization in vitro and distal peripheral nerve hyperexcitability when perlecan is lacking.
Bangratz M, Sarrazin N, Devaux J, Zambroni D, Echaniz-Laguna A, René F, Boërio D, Davoine CS, Fontaine B, Feltri ML, Benoit E, Nicole S. Bangratz M, et al. Among authors: sarrazin n. Am J Pathol. 2012 May;180(5):2040-55. doi: 10.1016/j.ajpath.2012.01.035. Epub 2012 Mar 23. Am J Pathol. 2012. PMID: 22449950 Free PMC article.
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