Liggett SB - Search Results

1

Pharmacogenomics of beta1-adrenergic receptor polymorphisms in heart failure.

Liggett SB. Liggett SB. Heart Fail Clin. 2010 Jan;6(1):27-33. doi: 10.1016/j.hfc.2009.08.011. Heart Fail Clin. 2010. PMID: 19945058 Free PMC article. Review.

2

A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure.

Liggett SB, Mialet-Perez J, Thaneemit-Chen S, Weber SA, Greene SM, Hodne D, Nelson B, Morrison J, Domanski MJ, Wagoner LE, Abraham WT, Anderson JL, Carlquist JF, Krause-Steinrauf HJ, Lazzeroni LC, Port JD, Lavori PW, Bristow MR. Liggett SB, et al. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11288-93. doi: 10.1073/pnas.0509937103. Epub 2006 Jul 14. Proc Natl Acad Sci U S A. 2006. PMID: 16844790 Free PMC article.

3

Differential coupling of Arg- and Gly389 polymorphic forms of the beta1-adrenergic receptor leads to pathogenic cardiac gene regulatory programs.

Swift SM, Gaume BR, Small KM, Aronow BJ, Liggett SB. Swift SM, et al. Among authors: liggett sb. Physiol Genomics. 2008 Sep 17;35(1):123-31. doi: 10.1152/physiolgenomics.90225.2008. Epub 2008 Jul 29. Physiol Genomics. 2008. PMID: 18664629 Free PMC article.

4

An alpha2C-adrenergic receptor polymorphism alters the norepinephrine-lowering effects and therapeutic response of the beta-blocker bucindolol in chronic heart failure.

Bristow MR, Murphy GA, Krause-Steinrauf H, Anderson JL, Carlquist JF, Thaneemit-Chen S, Krishnan V, Abraham WT, Lowes BD, Port JD, Davis GW, Lazzeroni LC, Robertson AD, Lavori PW, Liggett SB. Bristow MR, et al. Among authors: liggett sb. Circ Heart Fail. 2010 Jan;3(1):21-8. doi: 10.1161/CIRCHEARTFAILURE.109.885962. Epub 2009 Oct 30. Circ Heart Fail. 2010. PMID: 19880803

5

Variable-length poly-C tract polymorphisms of the beta2-adrenergic receptor 3'-UTR alter expression and agonist regulation.

Panebra A, Schwarb MR, Swift SM, Weiss ST, Bleecker ER, Hawkins GA, Liggett SB. Panebra A, et al. Among authors: liggett sb. Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L190-5. doi: 10.1152/ajplung.00277.2007. Epub 2007 Nov 16. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18024720 Free PMC article.

6

A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of beta2-adrenergic receptors.

Wang WC, Mihlbachler KA, Bleecker ER, Weiss ST, Liggett SB. Wang WC, et al. Among authors: liggett sb. Pharmacogenet Genomics. 2008 Aug;18(8):729-32. doi: 10.1097/FPC.0b013e32830967e9. Pharmacogenet Genomics. 2008. PMID: 18622265 Free PMC article.

7

Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway beta2-adrenergic receptor physiologic signaling.

Wang WC, Mihlbachler KA, Brunnett AC, Liggett SB. Wang WC, et al. Among authors: liggett sb. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15007-12. doi: 10.1073/pnas.0906034106. Epub 2009 Aug 17. Proc Natl Acad Sci U S A. 2009. PMID: 19706446 Free PMC article.

8

alpha2A-adrenergic receptors in the genetics, pathogenesis, and treatment of type 2 diabetes.

Liggett SB. Liggett SB. Sci Transl Med. 2009 Dec 23;1(12):12ps15. doi: 10.1126/scitranslmed.3000606. Sci Transl Med. 2009. PMID: 20371458 Review.

9

Bitransgenesis with beta(2)-adrenergic receptors or adenylyl cyclase fails to improve beta(1)-adrenergic receptor cardiomyopathy.

Petrashevskaya N, Gaume BR, Mihlbachler KA, Dorn GW 2nd, Liggett SB. Petrashevskaya N, et al. Among authors: liggett sb. Clin Transl Sci. 2008 Dec;1(3):221-7. doi: 10.1111/j.1752-8062.2008.00061.x. Clin Transl Sci. 2008. PMID: 20443853 Free PMC article.

10

Common ADRB2 haplotypes derived from 26 polymorphic sites direct beta2-adrenergic receptor expression and regulation phenotypes.

Panebra A, Wang WC, Malone MM, Pitter DR, Weiss ST, Hawkins GA, Liggett SB. Panebra A, et al. Among authors: liggett sb. PLoS One. 2010 Jul 29;5(7):e11819. doi: 10.1371/journal.pone.0011819. PLoS One. 2010. PMID: 20686604 Free PMC article.

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