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BACE1 and BACE2 enzymatic activities in Alzheimer's disease.
Ahmed RR, Holler CJ, Webb RL, Li F, Beckett TL, Murphy MP. Ahmed RR, et al. Among authors: webb rl. J Neurochem. 2010 Feb;112(4):1045-53. doi: 10.1111/j.1471-4159.2009.06528.x. Epub 2009 Dec 4. J Neurochem. 2010. PMID: 19968762 Free PMC article.
BACE2 expression increases in human neurodegenerative disease.
Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. Holler CJ, et al. Among authors: webb rl. Am J Pathol. 2012 Jan;180(1):337-50. doi: 10.1016/j.ajpath.2011.09.034. Epub 2011 Nov 7. Am J Pathol. 2012. PMID: 22074738 Free PMC article.
β-Secretases, Alzheimer's Disease, and Down Syndrome.
Webb RL, Murphy MP. Webb RL, et al. Curr Gerontol Geriatr Res. 2012;2012:362839. doi: 10.1155/2012/362839. Epub 2012 Feb 28. Curr Gerontol Geriatr Res. 2012. PMID: 22481915 Free PMC article.
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, Tosh JL, Siganporia C, Whittaker HT, Stewart F, Szaruga M; London Down syndrome consortium; Murphy MP, Blennow K, de Strooper B, Zetterberg H, Bannerman D, Holtzman DM, Tybulewicz VLJ, Fisher EMC; LonDownS Consortium. Wiseman FK, et al. Brain. 2018 Aug 1;141(8):2457-2474. doi: 10.1093/brain/awy159. Brain. 2018. PMID: 29945247 Free PMC article.
138 results