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Umbellulone modulates TRP channels.
Zhong J, Minassi A, Prenen J, Taglialatela-Scafati O, Appendino G, Nilius B. Zhong J, et al. Among authors: appendino g. Pflugers Arch. 2011 Dec;462(6):861-70. doi: 10.1007/s00424-011-1043-1. Epub 2011 Oct 29. Pflugers Arch. 2011. PMID: 22038323
Spices: the savory and beneficial science of pungency.
Nilius B, Appendino G. Nilius B, et al. Among authors: appendino g. Rev Physiol Biochem Pharmacol. 2013;164:1-76. doi: 10.1007/112_2013_11. Rev Physiol Biochem Pharmacol. 2013. PMID: 23605179 Review.
Ligustilide: a novel TRPA1 modulator.
Zhong J, Pollastro F, Prenen J, Zhu Z, Appendino G, Nilius B. Zhong J, et al. Among authors: appendino g. Pflugers Arch. 2011 Dec;462(6):841-9. doi: 10.1007/s00424-011-1021-7. Epub 2011 Sep 6. Pflugers Arch. 2011. PMID: 21894528
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.
Nassini R, Materazzi S, Vriens J, Prenen J, Benemei S, De Siena G, la Marca G, Andrè E, Preti D, Avonto C, Sadofsky L, Di Marzo V, De Petrocellis L, Dussor G, Porreca F, Taglialatela-Scafati O, Appendino G, Nilius B, Geppetti P. Nassini R, et al. Among authors: appendino g. Brain. 2012 Feb;135(Pt 2):376-90. doi: 10.1093/brain/awr272. Epub 2011 Oct 27. Brain. 2012. PMID: 22036959
272 results