Gütschow M - Search Results

1

In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.

Härtig W, Kacza J, Paulke BR, Grosche J, Bauer U, Hoffmann A, Elsinghorst PW, Gütschow M. Härtig W, et al. Among authors: gutschow m. Eur J Neurosci. 2010 Jan;31(1):99-109. doi: 10.1111/j.1460-9568.2009.07038.x. Epub 2009 Dec 21. Eur J Neurosci. 2010. PMID: 20092557

2

Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase.

Elsinghorst PW, Tanarro CM, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. J Med Chem. 2006 Dec 14;49(25):7540-4. doi: 10.1021/jm060742o. J Med Chem. 2006. PMID: 17149883

3

First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.

Elsinghorst PW, Cieslik JS, Mohr K, Tränkle C, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. J Med Chem. 2007 Nov 15;50(23):5685-95. doi: 10.1021/jm070859s. Epub 2007 Oct 18. J Med Chem. 2007. PMID: 17944454

4

A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid plaques.

Elsinghorst PW, Härtig W, Goldhammer S, Grosche J, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. Org Biomol Chem. 2009 Oct 7;7(19):3940-6. doi: 10.1039/b909612d. Epub 2009 Jul 17. Org Biomol Chem. 2009. PMID: 19763296

5

Direct formation of ring-fused 1,3-thiazine-2,4-dithiones from aromatic o-amino carboxylic acids: observation of a carbon disulfide mediated thionation.

Ottersbach PA, Elsinghorst PW, Häcker HG, Gütschow M. Ottersbach PA, et al. Among authors: gutschow m. Org Lett. 2010 Aug 20;12(16):3662-5. doi: 10.1021/ol101471g. Org Lett. 2010. PMID: 20666472

6

Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of sunitinib (SU11248) and its active metabolite, N-desethyl sunitinib (SU12662), in human plasma: application to an explorative study.

Rodamer M, Elsinghorst PW, Kinzig M, Gütschow M, Sörgel F. Rodamer M, et al. Among authors: gutschow m. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Apr 1;879(11-12):695-706. doi: 10.1016/j.jchromb.2011.02.006. Epub 2011 Feb 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21367676

7

The thermal and enzymatic taxifolin-alphitonin rearrangement.

Elsinghorst PW, Cavlar T, Müller A, Braune A, Blaut M, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. J Nat Prod. 2011 Oct 28;74(10):2243-9. doi: 10.1021/np200639s. Epub 2011 Oct 12. J Nat Prod. 2011. PMID: 21992235

8

A hydrazide linker strategy for heterobivalent compounds as ortho- and allosteric ligands of acetylcholine-binding proteins.

Elsinghorst PW, Härtig W, Gündisch D, Mohr K, Tränkle C, Gütschow M. Elsinghorst PW, et al. Among authors: gutschow m. Curr Top Med Chem. 2011 Nov;11(22):2731-48. doi: 10.2174/156802611798184427. Curr Top Med Chem. 2011. PMID: 22039876 Review.

9

A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity.

Mertens MD, Bierwisch A, Li T, Gütschow M, Thiermann H, Wille T, Elsinghorst PW. Mertens MD, et al. Among authors: gutschow m. Toxicol Lett. 2016 Feb 26;244:161-166. doi: 10.1016/j.toxlet.2015.10.012. Epub 2015 Oct 19. Toxicol Lett. 2016. PMID: 26494253

10

Chalcone Isomerase from Eubacterium ramulus Catalyzes the Ring Contraction of Flavanonols.

Braune A, Engst W, Elsinghorst PW, Furtmann N, Bajorath J, Gütschow M, Blaut M. Braune A, et al. Among authors: gutschow m. J Bacteriol. 2016 Oct 7;198(21):2965-2974. doi: 10.1128/JB.00490-16. Print 2016 Nov 1. J Bacteriol. 2016. PMID: 27551015 Free PMC article.

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