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Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. De Petrocellis L, et al. Among authors: vitale rm. J Med Chem. 2016 Jun 23;59(12):5661-83. doi: 10.1021/acs.jmedchem.5b01448. Epub 2016 Jun 14. J Med Chem. 2016. PMID: 27232526
In Silico Identification and Experimental Validation of Novel Anti-Alzheimer's Multitargeted Ligands from a Marine Source Featuring a "2-Aminoimidazole plus Aromatic Group" Scaffold.
Vitale RM, Rispoli V, Desiderio D, Sgammato R, Thellung S, Canale C, Vassalli M, Carbone M, Ciavatta ML, Mollo E, Felicità V, Arcone R, Gavagnin Capoggiani M, Masullo M, Florio T, Amodeo P. Vitale RM, et al. ACS Chem Neurosci. 2018 Jun 20;9(6):1290-1303. doi: 10.1021/acschemneuro.7b00416. Epub 2018 Mar 7. ACS Chem Neurosci. 2018. PMID: 29473731
Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.
Vitale RM, D'Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani ME, Fellous T, Gentile A, Carbone M, Cutignano A, Grauso L, Magliozzi L, Polese G, D'Aniello B, Defranoux F, Felline S, Terlizzi A, Calignano A, Regoli F, Di Marzo V, Amodeo P, Mollo E. Vitale RM, et al. Mar Drugs. 2018 Nov 3;16(11):431. doi: 10.3390/md16110431. Mar Drugs. 2018. PMID: 30400299 Free PMC article.
69 results