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In psychosis, cortical interneurons overexpress DNA-methyltransferase 1.
Veldic M, Guidotti A, Maloku E, Davis JM, Costa E. Veldic M, et al. Among authors: guidotti a. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2152-7. doi: 10.1073/pnas.0409665102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684088 Free PMC article.
Reelin promoter hypermethylation in schizophrenia.
Grayson DR, Jia X, Chen Y, Sharma RP, Mitchell CP, Guidotti A, Costa E. Grayson DR, et al. Among authors: guidotti a. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9341-6. doi: 10.1073/pnas.0503736102. Epub 2005 Jun 16. Proc Natl Acad Sci U S A. 2005. PMID: 15961543 Free PMC article.
Reelin down-regulation in mice and psychosis endophenotypes.
Tueting P, Doueiri MS, Guidotti A, Davis JM, Costa E. Tueting P, et al. Among authors: guidotti a. Neurosci Biobehav Rev. 2006;30(8):1065-77. doi: 10.1016/j.neubiorev.2006.04.001. Neurosci Biobehav Rev. 2006. PMID: 16769115 Review.
Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.
Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A. Agís-Balboa RC, et al. Among authors: guidotti a. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18736-41. doi: 10.1073/pnas.0709419104. Epub 2007 Nov 14. Proc Natl Acad Sci U S A. 2007. PMID: 18003893 Free PMC article.
Allopregnanolone (ALLO), synthesized by pyramidal neurons, is a potent positive allosteric modulator of the action of GABA at GABA(A) receptors expressing specific neurosteroid binding sites. ...In the cortex, hippocampus, and amygdala, these enzymes are colocalized …
Allopregnanolone (ALLO), synthesized by pyramidal neurons, is a potent positive allosteric modulator of the action of GABA at GABA( …
507 results