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Endoplasmic reticulum stress enhances γ-secretase activity.
Ohta K, Mizuno A, Li S, Itoh M, Ueda M, Ohta E, Hida Y, Wang MX, Furoi M, Tsuzuki Y, Sobajima M, Bohmoto Y, Fukushima T, Kobori M, Inuzuka T, Nakagawa T. Ohta K, et al. Among authors: ohta e. Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):362-6. doi: 10.1016/j.bbrc.2011.11.042. Epub 2011 Nov 16. Biochem Biophys Res Commun. 2011. PMID: 22115781
Cayman ataxia-related protein is a presynapse-specific caspase-3 substrate.
Itoh M, Li S, Ohta K, Yamada A, Hayakawa-Yano Y, Ueda M, Hida Y, Suzuki Y, Ohta E, Mizuno A, Banno Y, Nakagawa T. Itoh M, et al. Among authors: ohta e, ohta k. Neurochem Res. 2011 Jul;36(7):1304-13. doi: 10.1007/s11064-011-0430-5. Epub 2011 Mar 3. Neurochem Res. 2011. PMID: 21369758
Polyglutamine expansion disturbs the endoplasmic reticulum formation, leading to caspase-7 activation through Bax.
Ueda M, Li S, Itoh M, Hayakawa-Yano Y, Wang MX, Hayakawa M, Hasebe-Matsubara R, Ohta K, Ohta E, Mizuno A, Hida Y, Matsumoto M, Chen H, Nakagawa T. Ueda M, et al. Among authors: ohta e, ohta k. Biochem Biophys Res Commun. 2014 Jan 24;443(4):1232-8. doi: 10.1016/j.bbrc.2013.12.114. Epub 2014 Jan 2. Biochem Biophys Res Commun. 2014. PMID: 24388981
Cullin-4B E3 ubiquitin ligase mediates Apaf-1 ubiquitination to regulate caspase-9 activity.
Ohta E, Itoh M, Ueda M, Hida Y, Wang MX, Hayakawa-Ogura M, Li S, Nishida E, Ohta K, Tana, Islam S, Nakagawa K, Sunayama T, Chen H, Hirata S, Endo M, Ohno Y, Nakagawa T. Ohta E, et al. Among authors: ohta k. PLoS One. 2019 Jul 22;14(7):e0219782. doi: 10.1371/journal.pone.0219782. eCollection 2019. PLoS One. 2019. PMID: 31329620 Free PMC article.
183 results