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Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.
Martelli AM, Papa V, Tazzari PL, Ricci F, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Martinelli G, Ottaviani E, Pagliaro P, Horn S, Bäsecke J, Lindner LH, Eibl H, McCubrey JA. Martelli AM, et al. Among authors: papa v. Leukemia. 2010 Apr;24(4):687-98. doi: 10.1038/leu.2010.32. Epub 2010 Mar 4. Leukemia. 2010. PMID: 20200557
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Tazzari PL, Cappellini A, Ricci F, Evangelisti C, Papa V, Grafone T, Martinelli G, Conte R, Cocco L, McCubrey JA, Martelli AM. Tazzari PL, et al. Among authors: papa v. Leukemia. 2007 Mar;21(3):427-38. doi: 10.1038/sj.leu.2404523. Epub 2007 Jan 11. Leukemia. 2007. PMID: 17215852
281 results