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Structure and mechanism of human UDP-glucose 6-dehydrogenase.
Egger S, Chaikuad A, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: oppermann u. J Biol Chem. 2011 Jul 8;286(27):23877-87. doi: 10.1074/jbc.M111.234682. Epub 2011 Apr 18. J Biol Chem. 2011. PMID: 21502315 Free PMC article.
Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).
Yang SM, Yasgar A, Miller B, Lal-Nag M, Brimacombe K, Hu X, Sun H, Wang A, Xu X, Nguyen K, Oppermann U, Ferrer M, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ. Yang SM, et al. Among authors: oppermann u. J Med Chem. 2015 Aug 13;58(15):5967-78. doi: 10.1021/acs.jmedchem.5b00577. Epub 2015 Jul 24. J Med Chem. 2015. PMID: 26207746 Free PMC article.
Mechanism and substrate recognition of human holo ACP synthase.
Bunkoczi G, Pasta S, Joshi A, Wu X, Kavanagh KL, Smith S, Oppermann U. Bunkoczi G, et al. Among authors: oppermann u. Chem Biol. 2007 Nov;14(11):1243-53. doi: 10.1016/j.chembiol.2007.10.013. Chem Biol. 2007. PMID: 18022563 Free PMC article.
Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid.
Eixelsberger T, Sykora S, Egger S, Brunsteiner M, Kavanagh KL, Oppermann U, Brecker L, Nidetzky B. Eixelsberger T, et al. Among authors: oppermann u. J Biol Chem. 2012 Sep 7;287(37):31349-58. doi: 10.1074/jbc.M112.386706. Epub 2012 Jul 18. J Biol Chem. 2012. PMID: 22810237 Free PMC article.
257 results